HitPredict

Interactor 1: IHOG (Q9VM64)
Interference hedgehog
Gene: IHOG

Interactor 2: IHOG (Q9VM64)
Interference hedgehog
Gene: IHOG

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.802

The method score is based on:

Property Details
Experiments 31209108, 17077139
Identification Methods affinity chromatography technology, x-ray crystallography, molecular sieving, cosedimentation in solution
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, Ig_3~fn3, Ig_2~Ig_2, Ig_2~Ig_3, Ig_3~Ig_3
Common GO terms GO:0005113 - patched binding
GO:0005886 - plasma membrane
GO:0007224 - smoothened signaling pathway
GO:0007379 - segment specification
GO:0007411 - axon guidance
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 886
Dm

1 886
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Dm
+ Hs
+ Dr
+ Mm
+ Rn
+ Gg
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025