HitPredict

Interactor 1: SEM5C (Q9VTT0)
Semaphorin 5c
Gene: Sema5c

Interactor 2: Q9VVY7 (Q9VVY7)
FI20154p1
Gene: CG9600

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CUB~Sema, Ldl_recept_a~TSP_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1093 Dm			1 1260
+	Mm
		1021176 SEM3D_MOUSE (7-549): 5.99e-160: 494: 24.37		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		1021174 SEM6D_MOUSE (14-523): 1.06e-155: 492: 28.10		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Hs
		164336 SEM3A_HUMAN (23-558): 8.62e-159: 491: 22.24		NRP1_HUMAN (122-455): 7.29e-41: 165: 11.54
+	Mm
		148061 SEM3A_MOUSE (23-560): 1.05e-157: 489: 22.51		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		148057 SEM3A_MOUSE (23-560): 1.05e-157: 489: 22.51		NRP2_MOUSE (92-406): 1.99e-38: 158: 14.15
+	Mm
		1021167 Q0VGP2_MOUSE (29-553): 3.1e-151: 471: 24.08		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		1021173 SEM4C_MOUSE (23-549): 4.6e-149: 468: 24.73		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		204729 Q0VGP2_MOUSE (29-553): 3.1e-151: 471: 24.08		NRP2_MOUSE (92-406): 1.99e-38: 158: 14.15
+	Mm
		204873 SEM6A_MOUSE (27-553): 5.24e-144: 460: 26.90		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		999975 SEM3E_MOUSE (49-550): 8.2e-147: 460: 24.31		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		148766 SEM4D_MOUSE (24-571): 2.82e-145: 459: 23.77		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Hs
		164426 SEM3C_HUMAN (50-548): 3.4e-147: 460: 24.86		NRP1_HUMAN (122-455): 7.29e-41: 165: 11.54
+	Mm
		1021172 SEM3C_MOUSE (50-548): 1.57e-145: 456: 24.68		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		204728 SEM3E_MOUSE (49-550): 8.2e-147: 460: 24.31		NRP2_MOUSE (92-406): 1.99e-38: 158: 14.15
+	Mm
		204733 SEM3C_MOUSE (50-548): 1.57e-145: 456: 24.68		NRP2_MOUSE (92-406): 1.99e-38: 158: 14.15
+	Mm
		312732 SEM3F_MOUSE (18-553): 3.04e-137: 435: 23.94		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		204725 SEM3F_MOUSE (18-553): 3.04e-137: 435: 23.94		NRP2_MOUSE (92-406): 1.99e-38: 158: 14.15
+	Hs
		249042 SEM3F_HUMAN (17-553): 2.85e-137: 435: 24.39		NRP2_HUMAN (92-406): 1.62e-38: 158: 14.15
+	Mm
		1021181 SEM6C_MOUSE (36-561): 8.9e-132: 425: 26.63		NRP1_MOUSE (120-459): 5.86e-41: 166: 12.86
+	Mm
		204732 SEM4B_MOUSE (48-555): 8.19e-132: 422: 23.24		NRP2_MOUSE (92-406): 1.99e-38: 158: 14.15