Protein: NRP2
Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2)

Gene: NRP2
Organism: Homo sapiens
Interactions: 58
UniProt ID: O60462

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002116 - semaphorin receptor complex
GO:0003148 - outflow tract septum morphogenesis
GO:0005021 - vascular endothelial growth factor receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

249023

NRP2
Neuropilin-2

3

15

Small-scale

0.867

High

249030

VEGFA
Vascular endothelial growth factor A, long form

2

7

Small-scale

0.778

High

249032

CEAM8
Cell adhesion molecule CEACAM8

1

3

High-throughput

0.691

High

249059

TMPSD
Transmembrane protease serine 13

1

20

High-throughput

0.691

High

249070

ST14
Suppressor of tumorigenicity 14 protein

1

20

High-throughput

0.691

High

249037

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

3

2

High-throughput

0.667

High

249040

NAAA
N-acylethanolamine-hydrolyzing acid amidase

3

2

High-throughput

0.667

High

249024

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

3

4

High-throughput

0.656

High

249042

SEM3F
Semaphorin-3F

1

20

Small-scale

0.647

High

249025

NXPH2
Neurexophilin-2

3

0

High-throughput

0.638

High

50755

TSN11
Tetraspanin-11

2

4

High-throughput

0.628

High

249039

DEF5
Defensin alpha 5

2

3

High-throughput

0.628

High

249050

LYZL1
Lysozyme-like protein 1

2

2

High-throughput

0.628

High

249056

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

2

High-throughput

0.628

High

164193

NRP1
Neuropilin-1

1

16

Small-scale

0.621

High

208109

PLXB1
Plexin-B1

1

20

Small-scale

0.621

High

249033

L1CAM
Neural cell adhesion molecule L1

1

2

Small-scale

0.621

High

249066

PLXA1
Plexin-A1

1

20

Small-scale

0.621

High

249036

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.618

High

249034

RYK
Tyrosine-protein kinase RYK

2

8

Small-scale

0.611

High

249045

TAZ
Tafazzin

3

1

High-throughput

0.609

High

249052

BRNP3
BMP/retinoic acid-inducible neural-specific protein 3

2

0

High-throughput

0.602

High

209365

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

2

2

High-throughput

0.574

High

249061

SIAE
Sialate O-acetylesterase

2

1

High-throughput

0.558

High

139157

UPK2
Uroplakin-2

1

1

High-throughput

0.536

High

248457

O10H2
Olfactory receptor 10H2

1

1

High-throughput

0.536

High

249027

C1QA
Complement C1q subcomponent subunit A

1

14

High-throughput

0.536

High

249028

CCL3
C-C motif chemokine 3

1

5

High-throughput

0.536

High

249031

CALX
Calnexin

1

9

High-throughput

0.536

High

249038

DEF1
Neutrophil defensin 1

1

3

High-throughput

0.536

High

249041

NKG2E
NKG2-E type II integral membrane protein

1

12

High-throughput

0.536

High

249060

CSTL1
Cystatin-like 1

1

2

High-throughput

0.536

High

249065

COKA1

1

5

High-throughput

0.536

High

249068

PCDGD
Protocadherin gamma-B1

1

3

High-throughput

0.536

High

249046

DB135
Beta-defensin 135

1

0

High-throughput

0.513

High

249054

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

249058

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

249043

SG2A2
Mammaglobin-A

1

3

High-throughput

0.489

High

217577

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

249035

TGFR2
TGF-beta receptor type-2

1

3

Small-scale

0.479

High

249067

SNX6
Sorting nexin-6

1

5

High-throughput

0.479

High

222564

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

249063

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

97122

E9PNY5
Fc gamma receptor IIIb

1

1

High-throughput

0.445

High

249029

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

3

High-throughput

0.445

High

249047

S39AC
Zinc transporter ZIP12

1

3

High-throughput

0.445

High

249048

NTCP5
Sodium/bile acid cotransporter 5

1

1

High-throughput

0.445

High

249055

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.445

High

249064

S22AB
Solute carrier family 22 member 11

1

4

High-throughput

0.445

High

249044

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

249051

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

249069

SNX5
Sorting nexin-5

1

5

High-throughput

0.437

High

249026

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

249062

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

249053

S22A9
Organic anion transporter 7

1

4

High-throughput

0.407

High

249049

TRI68
E3 ubiquitin-protein ligase TRIM68

1

0

High-throughput

0.279

Low

249057

S35B4
Nucleotide sugar transporter SLC35B4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025