HitPredict

Interactor 1: NET1 (O09118)
Netrin-1
Gene: Ntn1

Interactor 2: DCC (P70211)
Netrin receptor DCC (Tumor suppressor protein DCC)
Gene: DCC

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	18585357
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Laminin_EGF~fn3, Laminin_N~fn3
Common GO terms	GO:0001764 - neuron migration GO:0006915 - apoptotic process GO:0033564 - anterior/posterior axon guidance
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 604 Mm			1 1447
+	Hs
		340701 NET1_HUMAN (1-604): 3.74e-180: 524: 99.17		DCC_HUMAN (1-1447): 0: 984: 96.48
+	Dr
		205887 O42140_DANRE (2-604): 0: 533: 85.90		Q49BB0_DANRE (5-1447): 0: 879: 70.24
+	Dr
		3195 O42140_DANRE (2-604): 0: 533: 85.90		A0A0R4IP15_DANRE (12-1443): 0: 828: 49.17
+	Dr
		3194 F1QUK5_DANRE (2-601): 1.65e-176: 515: 80.40		A0A0R4IP15_DANRE (12-1443): 0: 828: 49.17
+	Mm
		999934 NET4_MOUSE (9-597): 1.18e-105: 333: 28.55		DCC_MOUSE (1-1447): 0: 997: 100.00
+	Hs
		845993 NET4_HUMAN (9-598): 1.33e-107: 338: 28.51		DCC_HUMAN (1-1447): 0: 984: 96.48
+	Mm
		148764 NET1_MOUSE (1-604): 4.7e-180: 524: 100.00		DSCAM_MOUSE (17-1392): 1.07e-98: 352: 14.00
+	Dm
		55065 NETB_DROME (32-254): 3.19e-58: 210: 54.24		A1Z921_DROME (17-1447): 0: 621: 29.34
+	Hs
		340709 NET1_HUMAN (1-604): 3.74e-180: 524: 99.17		NEO1_HUMAN (14-726): 2.3e-55: 214: 14.75
+	Hs
		1369596 NET4_HUMAN (9-598): 1.33e-107: 338: 28.51		NEO1_HUMAN (14-726): 2.3e-55: 214: 14.75
+	Mm
		1190770 NET5_MOUSE (341-602): 7.33e-53: 189: 38.27		DSCAM_MOUSE (17-1392): 1.07e-98: 352: 14.00
+	Dm
		1175507 NETB_DROME (32-254): 3.19e-58: 210: 54.24		Q9W213_DROME (33-627): 1.82e-19: 97.4: 24.01
+	Dm
		1175013 NETB_DROME (32-254): 3.19e-58: 210: 54.24		Q94538_DROME (10-533): 6.26e-11: 69.8: 10.68