HitPredict

Interactor 1: NET1 (O09118)
Netrin-1
Gene: Ntn1

Interactor 2: DSCAM (Q9ERC8)
Cell adhesion molecule DSCAM (Down syndrome cell adhesion molecule homolog)
Gene: DSCAM

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	26633812, 18585357
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Laminin_EGF~fn3, Laminin_N~fn3
Common GO terms	GO:0007411 - axon guidance GO:0045202 - synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 604 Mm			1 2013
+	Mm
		1190770 NET5_MOUSE (341-602): 7.33e-53: 189: 38.27		DSCAM_MOUSE (1-2013): 0: 1307: 100.00
+	Mm
		148760 NET1_MOUSE (1-604): 4.7e-180: 524: 100.00		DCC_MOUSE (5-988): 1.53e-90: 328: 16.11
+	Hs
		340701 NET1_HUMAN (1-604): 3.74e-180: 524: 99.17		DCC_HUMAN (1-988): 1.26e-88: 322: 15.34
+	Dr
		3195 O42140_DANRE (2-604): 0: 533: 85.90		A0A0R4IP15_DANRE (903-1998): 4.99e-62: 237: 14.94
+	Dr
		3194 F1QUK5_DANRE (2-601): 1.65e-176: 515: 80.40		A0A0R4IP15_DANRE (903-1998): 4.99e-62: 237: 14.94
+	Dr
		205887 O42140_DANRE (2-604): 0: 533: 85.90		Q49BB0_DANRE (13-415): 5.45e-47: 188: 19.58
+	Mm
		999934 NET4_MOUSE (9-597): 1.18e-105: 333: 28.55		DCC_MOUSE (5-988): 1.53e-90: 328: 16.11
+	Hs
		845993 NET4_HUMAN (9-598): 1.33e-107: 338: 28.51		DCC_HUMAN (1-988): 1.26e-88: 322: 15.34
+	Hs
		340709 NET1_HUMAN (1-604): 3.74e-180: 524: 99.17		NEO1_HUMAN (19-532): 8.38e-26: 119: 13.86
+	Hs
		1369596 NET4_HUMAN (9-598): 1.33e-107: 338: 28.51		NEO1_HUMAN (19-532): 8.38e-26: 119: 13.86
+	Dm
		1175507 NETB_DROME (32-254): 3.19e-58: 210: 54.24		Q9W213_DROME (100-506): 9.97e-26: 118: 27.57
+	Hs
		673763 LAMA1_HUMAN (394-575): 6.07e-09: 61.4: 11.50		PGBM_HUMAN (677-813): 6.12e-09: 63.6: 18.25