HitPredict

Interactor 1: DVL1 (O14640)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24469800
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016328 - lateral plasma membrane GO:0043025 - neuronal cell body
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 695 Hs			1 2115
+	Hs
		1061195 DVL3_HUMAN (1-695): 1.01e-153: 463: 61.00		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		150996 DVL2_HUMAN (3-695): 1.59e-140: 430: 55.84		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1068623 DVL3_HUMAN (1-695): 1.01e-153: 463: 61.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		1067454 DVL3_HUMAN (1-695): 1.01e-153: 463: 61.00		EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15
+	Hs
		150837 DVL2_HUMAN (3-695): 1.59e-140: 430: 55.84		MYH7_HUMAN (947-2023): 1.11e-36: 155: 11.21
+	Hs
		151001 DVL2_HUMAN (3-695): 1.59e-140: 430: 55.84		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		150999 DVL2_HUMAN (3-695): 1.59e-140: 430: 55.84		EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15
+	Hs
		876385 AFAD_HUMAN (246-658): 1.91e-82: 288: 20.83		GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49
+	Mm
		1164008 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		MYH9_MOUSE (1089-2070): 6.61e-40: 165: 12.96
+	Mm
		1164088 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		PLEC_MOUSE (21-1207): 2.95e-35: 150: 12.47
+	Mm
		1132056 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		MYH4_MOUSE (1-831): 5.49e-35: 149: 12.50
+	Rn
		192527 NEB2_RAT (75-423): 3.82e-49: 186: 15.89		MYH10_RAT (1281-2075): 2.06e-32: 140: 12.22
+	Hs
		724975 NEB2_HUMAN (75-423): 2.81e-47: 181: 15.34		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Mm
		1143165 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		MYH10_MOUSE (5-834): 3.93e-31: 136: 11.65
+	Hs
		724903 RIMS1_HUMAN (8-675): 6.11e-45: 175: 14.18		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		725194 RIMS1_HUMAN (8-675): 6.11e-45: 175: 14.18		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Mm
		93873 NEB2_MOUSE (75-423): 2.88e-48: 184: 15.62		E9QPE7_MOUSE (1396-1867): 9.42e-16: 86.2: 13.90
+	Hs
		724845 DIXC1_HUMAN (4-81): 3.14e-26: 116: 42.31		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62