HitPredict

Interactor 1: CHD1 (O14646)
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)
Gene: CHD1

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	34079125, 36089195, 16372014
Identification Methods	proximity labelling technology, x-ray crystallography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1710 Hs			1 136
+	Hs
		151419 CHD1_HUMAN (1-1710): 0: 1217: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		151399 CHD1_HUMAN (1-1710): 0: 1217: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Mm
		770296 CHD1_MOUSE (1-1710): 0: 1217: 94.51		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Hs
		151392 CHD1_HUMAN (1-1710): 0: 1217: 100.00		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		151487 CHD2_HUMAN (2-1710): 0: 1037: 54.45		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Dm
		356088 CHD1_DROME (22-1709): 0: 1016: 43.89		H3_DROME (1-136): 6.5e-61: 185: 99.27
+	Hs
		934705 CHD3_HUMAN (32-1512): 0: 913: 25.34		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		952302 CHD3_HUMAN (32-1512): 0: 913: 25.34		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		935262 CHD8_HUMAN (30-1354): 0: 871: 25.62		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		828213 CHD3_HUMAN (32-1512): 0: 913: 25.34		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		952639 CHD8_HUMAN (30-1354): 0: 871: 25.62		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Mm
		56901 CHD5_MOUSE (73-1403): 0: 869: 26.05		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Hs
		935016 CHD5_HUMAN (131-1386): 0: 861: 26.76		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086233 CHD5_HUMAN (131-1386): 0: 861: 26.76		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		934770 CHD4_HUMAN (84-1512): 0: 839: 24.61		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1059646 CHD4_HUMAN (84-1512): 0: 839: 24.61		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952343 CHD4_HUMAN (84-1512): 0: 839: 24.61		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		1059689 CHD4_HUMAN (84-1512): 0: 839: 24.61		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		1059677 CHD4_HUMAN (84-1512): 0: 839: 24.61		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Sp
		144536 HRP3_SCHPO (118-1504): 0: 818: 33.82		H31_SCHPO (1-136): 3.54e-59: 181: 91.91