Protein: FIP1
Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia)

Gene: FIP1, FIP1L1
Organism: Homo sapiens
Interactions: 212
UniProt ID: Q6UN15

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

340756

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

8

6

Small-scale

0.974

High

66973

CPS4L
Putative cleavage and polyadenylation specificity factor subunit 4-like protein

3

6

High-throughput

0.861

High

372353

MYC
Myc proto-oncogene protein

5

3

High-throughput

0.702

High

1083389

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

4

2

Small-scale

0.698

High

1248090

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

4

4

Small-scale

0.694

High

1248075

WDR33
pre-mRNA 3' end processing protein WDR33

4

2

Small-scale

0.683

High

1248033

ZCH18
Zinc finger CCCH domain-containing protein 18

3

2

High-throughput

0.667

High

1248094

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

3

4

Small-scale

0.667

High

191346

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

3

2

High-throughput

0.662

High

1248078

CSTFT
Cleavage stimulation factor subunit 2 tau variant

3

5

Small-scale

0.650

High

938111

ANM2
Protein arginine N-methyltransferase 2

2

2

High-throughput

0.620

High

1092326

CSTF3
Cleavage stimulation factor subunit 3

2

3

Small-scale

0.619

High

1248024

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

2

High-throughput

0.618

High

1248068

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.618

High

132112

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

2

High-throughput

0.611

High

485217

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

2

Small-scale

0.611

High

1248052

SYMPK
Symplekin

2

1

High-throughput

0.611

High

260100

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

345966

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.584

High

1248089

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.582

High

567008

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

2

2

High-throughput

0.574

High

1092447

TIAM1
Rho guanine nucleotide exchange factor TIAM1

2

1

High-throughput

0.571

High

1198130

RHG29
Rho GTPase-activating protein 29

2

3

High-throughput

0.571

High

1217687

SYDE2
Rho GTPase-activating protein SYDE2

2

3

High-throughput

0.571

High

1248096

VAV3
Guanine nucleotide exchange factor VAV3

2

1

High-throughput

0.571

High

997803

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.550

High

833644

NAA10
N-alpha-acetyltransferase 10

1

0

High-throughput

0.549

High

478092

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.536

High

480197

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

625450

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

714208

PML
Protein PML

1

1

High-throughput

0.536

High

750431

CSTF2
Cleavage stimulation factor subunit 2

1

5

High-throughput

0.536

High

854124

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

889593

CLK2
Dual specificity protein kinase CLK2

1

2

High-throughput

0.536

High

945710

FOXL2
Forkhead box protein L2

1

1

High-throughput

0.536

High

966490

1433G
14-3-3 protein gamma

1

5

High-throughput

0.536

High

1050292

CSTF1
Cleavage stimulation factor subunit 1

1

1

High-throughput

0.536

High

1160175

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

4

High-throughput

0.536

High

1240999

L2GL2
LLGL scribble cell polarity complex component 2

1

1

High-throughput

0.536

High

1248049

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

2

High-throughput

0.536

High

1248067

RBM14
RNA-binding protein 14

1

1

High-throughput

0.536

High

1063359

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.523

High

122792

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

175088

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.513

High

251603

CCNT1
Cyclin-T1

1

0

High-throughput

0.513

High

452301

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.513

High

1111054

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1248031

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.513

High

1248053

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

1248059

CDCA5
Sororin

1

0

High-throughput

0.513

High

1248083

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

1248091

POLK
DNA polymerase kappa

1

0

High-throughput

0.513

High

1248095

HDAC9
Histone deacetylase 9

1

0

High-throughput

0.513

High

481315

HMGB1
High mobility group protein B1

1

3

High-throughput

0.508

High

1248064

ANM6
Protein arginine N-methyltransferase 6

1

2

High-throughput

0.508

High

899751

PAPOA
Poly(A) polymerase alpha

1

5

Small-scale

0.501

High

1006486

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.501

High

1248074

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

2

High-throughput

0.500

High

1137354

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

1155475

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.493

High

471095

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.489

High

226805

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

1

High-throughput

0.481

High

185788

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

422374

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1240638

CDC73
Parafibromin

1

0

Small-scale

0.479

High

129748

CBX4
E3 SUMO-protein ligase CBX4

1

1

High-throughput

0.479

High

172971

XPO1
Exportin-1

1

2

High-throughput

0.479

High

212265

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.479

High

228290

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

High-throughput

0.479

High

280674

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.479

High

315704

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

331065

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

370702

FOS
Protein c-Fos

1

1

High-throughput

0.479

High

396360

ESR1
Estrogen receptor

1

6

Small-scale

0.479

High

401017

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

406302

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

472831

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

7

High-throughput

0.479

High

487449

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

542079

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.479

High

588966

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

606863

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

675551

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

768474

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

786678

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

High-throughput

0.479

High

889128

RBM25
RNA-binding protein 25

1

5

High-throughput

0.479

High

891634

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.479

High

897871

CDK9
Cyclin-dependent kinase 9

1

3

High-throughput

0.479

High

904852

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

937792

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

979860

H4
Histone H4

1

1

High-throughput

0.479

High

1024648

VIGLN
Vigilin

1

2

High-throughput

0.479

High

1067444

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1088406

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

1094572

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

1

High-throughput

0.479

High

1109152

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

2

High-throughput

0.479

High

1113456

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1128034

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.479

High

1132771

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1137791

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

1140447

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1148510

SF3B4
Splicing factor 3B subunit 4

1

1

High-throughput

0.479

High

1213056

RHG21
Rho GTPase-activating protein 21

1

3

High-throughput

0.479

High

1226907

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1241260

TAF2
Transcription initiation factor TFIID subunit 2

1

1

High-throughput

0.479

High

1242413

RHGBA
Rho GTPase-activating protein 11A

1

1

High-throughput

0.479

High

1248025

WDR82
WD repeat-containing protein 82

1

5

High-throughput

0.479

High

1248036

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.479

High

1248037

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1248038

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

3

High-throughput

0.479

High

1248039

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

1248044

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1248045

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

1

High-throughput

0.479

High

1248046

ATX2L
Ataxin-2-like protein

1

2

High-throughput

0.479

High

1248047

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.479

High

1248054

FUBP1
Far upstream element-binding protein 1

1

1

High-throughput

0.479

High

1248058

RNF31
E3 ubiquitin-protein ligase RNF31

1

2

High-throughput

0.479

High

1248069

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

1248071

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

1248073

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1248077

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.479

High

1248085

RNC
Ribonuclease 3

1

2

High-throughput

0.479

High

1248087

DCA13
DDB1- and CUL4-associated factor 13

1

2

High-throughput

0.479

High

1248088

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

High-throughput

0.479

High

1248092

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1248097

RHG26
Rho GTPase-activating protein 26

1

2

High-throughput

0.479

High

1248098

SRRM2
Serine/arginine repetitive matrix protein 2

1

2

High-throughput

0.479

High

1248099

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

892687

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

129198

MEN1
Menin

1

0

High-throughput

0.458

High

134779

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

157522

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

223135

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

227594

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

272272

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

319852

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

349129

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

375637

RASK
GTPase KRas

1

0

High-throughput

0.458

High

657608

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

695751

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

809689

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

867220

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

877150

KC1D
Casein kinase I isoform delta

1

0

High-throughput

0.458

High

935540

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

965038

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

970674

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

992598

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1029862

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1045422

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1124627

SRC8
Src substrate cortactin

1

0

High-throughput

0.458

High

1134956

CUL7
Cullin-7

1

0

High-throughput

0.458

High

1205061

FA76B
Protein FAM76B

1

0

High-throughput

0.458

High

1215672

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

1248028

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1248030

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1248032

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

1248035

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

1248040

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

1248042

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1248043

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1248048

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1248056

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1248060

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

1248062

EAF1
ELL-associated factor 1

1

0

High-throughput

0.458

High

1248065

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1248070

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1248072

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1248081

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1248086

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

430053

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

765636

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

911621

NCBP2
Nuclear cap-binding protein subunit 2

1

7

High-throughput

0.445

High

1016484

SRSF3
Serine/arginine-rich splicing factor 3

1

8

High-throughput

0.445

High

1145239

RNPS1
RNA-binding protein with serine-rich domain 1

1

2

High-throughput

0.445

High

1203169

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

1226140

CP135
Centrosomal protein of 135 kDa

1

1

High-throughput

0.445

High

1248026

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.445

High

1248050

ESR2
Estrogen receptor beta

1

6

High-throughput

0.445

High

1248066

CEP63
Centrosomal protein of 63 kDa

1

2

High-throughput

0.445

High

1248093

DDX41
Probable ATP-dependent RNA helicase DDX41

1

1

High-throughput

0.445

High

1248051

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.438

High

318495

TOX4
TOX high mobility group box family member 4

1

3

High-throughput

0.437

High

1141185

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.437

High

1248029

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1248079

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

344223

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

442751

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

756242

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.426

High

1066689

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

1248082

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1248084

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.426

High

886973

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

1228968

RNF43
E3 ubiquitin-protein ligase RNF43

2

0

High-throughput

0.305

High

1248057

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

High-throughput

0.299

High

292010

CRTAP
Cartilage-associated protein

1

0

High-throughput

0.279

Low

873400

LSS
Lanosterol synthase

1

0

High-throughput

0.279

Low

1248034

TSYL5
Testis-specific Y-encoded-like protein 5

1

0

High-throughput

0.279

Low

1248055

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.279

Low

1248076

NUAK2
NUAK family SNF1-like kinase 2

1

0

High-throughput

0.279

Low

1248080

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.279

Low

276145

NIPS2
Protein NipSnap homolog 2

1

0

Small-scale

0.249

Low

293883

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

412123

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

720495

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

1025926

NDP
Norrin

1

0

Small-scale

0.249

Low

1071167

ARL16
ADP-ribosylation factor-like protein 16

1

0

High-throughput

0.249

Low

1233831

GRAM4
GRAM domain-containing protein 4

1

0

Small-scale

0.249

Low

1248027

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1248041

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1248061

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

62542

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

1248063

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025