HitPredict

Interactor 1: CHD1 (O14646)
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)
Gene: CHD1

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	12890497
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1710 Hs			1 164
+	Hs
		1018508 CHD3_HUMAN (32-1512): 0: 913: 25.34		SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35
+	Hs
		703377 CHD3_HUMAN (32-1512): 0: 913: 25.34		CSTF2_HUMAN (10-110): 1.87e-25: 103: 25.47
+	Hs
		951935 CHD3_HUMAN (32-1512): 0: 913: 25.34		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		992741 CHD3_HUMAN (32-1512): 0: 913: 25.34		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		1018454 CHD3_HUMAN (32-1512): 0: 913: 25.34		SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34
+	Hs
		1018458 CHD3_HUMAN (32-1512): 0: 913: 25.34		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516483 CHD3_HUMAN (32-1512): 0: 913: 25.34		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		1018455 CHD3_HUMAN (32-1512): 0: 913: 25.34		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44
+	Hs
		516702 CHD8_HUMAN (30-1354): 0: 871: 25.62		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		1059643 CHD4_HUMAN (84-1512): 0: 839: 24.61		SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35
+	Hs
		951965 CHD4_HUMAN (84-1512): 0: 839: 24.61		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		992774 CHD4_HUMAN (84-1512): 0: 839: 24.61		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		1028656 CHD4_HUMAN (84-1512): 0: 839: 24.61		SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34
+	Hs
		1031332 CHD4_HUMAN (84-1512): 0: 839: 24.61		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516522 CHD4_HUMAN (84-1512): 0: 839: 24.61		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		1028548 CHD4_HUMAN (84-1512): 0: 839: 24.61		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Hs
		1028915 CHD4_HUMAN (84-1512): 0: 839: 24.61		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44
+	Dm
		332738 CHDM_DROME (23-1509): 0: 813: 24.02		SRR55_DROME (11-89): 1.88e-16: 77: 46.84
+	Zm
		18681 A0A1D6MT91_MAIZE (353-1376): 0: 761: 30.43		A0A1D6H7I7_MAIZE (10-163): 3.59e-27: 105: 29.59
+	Dm
		1097620 ISWI_DROME (365-1376): 0: 756: 27.62		RX21_DROME (10-81): 7.87e-22: 88.6: 54.17