HitPredict

Interactor 1: GOSR2 (O14653)
Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin)
Gene: GOSR2

Interactor 2: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	30833792, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Synaptobrevin~V-SNARE_C
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 212 Hs			1 116
+	Rn
		192340 GOSR2_RAT (1-212): 1.8e-63: 197: 91.04		SC22B_RAT (2-86): 2.38e-23: 91.1: 17.65
+	Hs
		306842 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00
+	Hs
		151535 GOSR2_HUMAN (1-212): 5.78e-61: 191: 100.00		VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58
+	Dm
		1178131 GOSR2_DROME (1-211): 5.02e-53: 171: 41.12		Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18
+	Hs
		151536 GOSR2_HUMAN (1-212): 5.78e-61: 191: 100.00		SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65
+	Dm
		577252 GOSR2_DROME (1-211): 5.02e-53: 171: 41.12		SYB_DROME (2-88): 9.74e-30: 105: 39.08
+	At
		221565 VTI11_ARATH (1-191): 2.81e-50: 164: 14.36		VA711_ARATH (4-95): 5.3e-28: 103: 22.58
+	Hs
		306885 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00
+	Rn
		1144366 VTI1A_RAT (2-211): 8.36e-52: 168: 12.09		VAMP1_RAT (2-78): 9.26e-27: 97.3: 37.66
+	Hs
		261703 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58
+	Dm
		1178140 Q9W0N6_DROME (1-212): 7.2e-45: 150: 17.89		Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18
+	Hs
		1284295 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		VAMP8_HUMAN (2-74): 9.04e-26: 94.2: 26.03
+	Hs
		263321 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65
+	Hs
		1079397 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03
+	Mm
		291513 VTI1B_MOUSE (2-210): 1.26e-49: 162: 14.88		VAMP7_MOUSE (4-94): 1.74e-25: 96.9: 31.87
+	Dm
		577264 Q9W0N6_DROME (1-212): 7.2e-45: 150: 17.89		SYB_DROME (2-88): 9.74e-30: 105: 39.08
+	Hs
		850604 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18
+	Hs
		261737 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58
+	Hs
		263387 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65
+	Hs
		1079465 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03