HitPredict

Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.629

The method score is based on:

Property Details
Experiments 21502505, 16603732
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0043627 - response to estrogen
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 5537
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024