Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5

Interactor 2: RIOK1 (Q9BRS2)
Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)
Gene: RIOK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 21081503, 33624332, 25852190, 29384474, 35271311, 32707033
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, unspecified method, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 637
Hs

1 568
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024