Protein: ARK74
Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like)

Gene: ARK74, AKR7L
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q8NHP1

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326895

ARK73
Aldo-keto reductase family 7 member A3

3

16

High-throughput

0.789

High

217276

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

15

High-throughput

0.575

High

1340181

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.575

High

238925

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

2

High-throughput

0.445

High

251317

NEMF
Ribosome quality control complex subunit NEMF

1

1

High-throughput

0.445

High

692099

MARK3
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.445

High

770025

RFC1
Replication factor C subunit 1

1

2

High-throughput

0.445

High

1040338

DYST
Dystonin

1

4

High-throughput

0.445

High

1207409

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.445

High

1251387

GGYF2
GRB10-interacting GYF protein 2

1

2

High-throughput

0.445

High

1270477

MARK2
Serine/threonine-protein kinase MARK2

1

2

High-throughput

0.445

High

1278768

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.445

High

1294404

SPAS2
Spermatogenesis-associated serine-rich protein 2

1

1

High-throughput

0.445

High

1340176

DDX55
ATP-dependent RNA helicase DDX55

1

1

High-throughput

0.445

High

1340177

PARD3
Partitioning defective 3 homolog

1

3

High-throughput

0.445

High

1340178

PNISR
Arginine/serine-rich protein PNISR

1

1

High-throughput

0.445

High

1340179

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

1

High-throughput

0.445

High

1340189

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.445

High

1340190

SRPK1
SRSF protein kinase 1

1

6

High-throughput

0.445

High

1340192

RIOK1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.445

High

1340194

RIOK2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.445

High

1340195

SRRT
Serrate RNA effector molecule homolog

1

3

High-throughput

0.445

High

1340200

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

3

High-throughput

0.445

High

1340202

RENT2
Regulator of nonsense transcripts 2

1

2

High-throughput

0.445

High

1340203

NXT2
NTF2-related export protein 2

1

4

High-throughput

0.445

High

1340204

SPS2L
SPATS2-like protein

1

1

High-throughput

0.445

High

1340205

PEF1
Peflin

1

2

High-throughput

0.445

High

1340206

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

4

High-throughput

0.445

High

122815

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.426

High

191006

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.426

High

270964

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.426

High

324995

HEXI1
Protein HEXIM1

1

0

High-throughput

0.426

High

594851

GCFC2
Intron Large complex component GCFC2

1

0

High-throughput

0.426

High

1008636

MAP1A
Microtubule-associated protein 1A

1

0

High-throughput

0.426

High

1130790

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.426

High

1151360

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.426

High

1193651

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.426

High

1218815

FOCAD
Focadhesin

1

0

High-throughput

0.426

High

1254261

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.426

High

1292170

LIPB1
Liprin-beta-1

1

0

High-throughput

0.426

High

1340180

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.426

High

1340184

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.426

High

1340191

STRBP
Spermatid perinuclear RNA-binding protein

1

0

High-throughput

0.426

High

1340196

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.426

High

1340197

REN3B
Regulator of nonsense transcripts 3B

1

0

High-throughput

0.426

High

188507

NVL
Nuclear valosin-containing protein-like

1

9

High-throughput

0.407

High

1311811

DHX40
Probable ATP-dependent RNA helicase DHX40

1

4

High-throughput

0.407

High

1340182

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

3

High-throughput

0.407

High

1340199

DDX47
Probable ATP-dependent RNA helicase DDX47

1

1

High-throughput

0.407

High

1340208

DDX49
Probable ATP-dependent RNA helicase DDX49

1

1

High-throughput

0.407

High

87508

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

294988

RPP40
Ribonuclease P protein subunit p40

1

0

High-throughput

0.232

Low

329773

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

0

High-throughput

0.232

Low

569126

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.232

Low

770404

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.232

Low

829119

RFC5
Replication factor C subunit 5

1

0

High-throughput

0.232

Low

1005482

RBM6
RNA-binding protein 6

1

0

High-throughput

0.232

Low

1005752

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.232

Low

1124378

ELOA1
Elongin-A

1

0

High-throughput

0.232

Low

1270752

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.232

Low

1272242

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.232

Low

1290011

PNM8A
Paraneoplastic antigen-like protein 8A

1

0

High-throughput

0.232

Low

1337401

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.232

Low

1340183

GPKOW
G-patch domain and KOW motifs-containing protein

1

0

High-throughput

0.232

Low

1340185

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.232

Low

1340186

CSTOS
Protein CUSTOS

1

0

High-throughput

0.232

Low

1340187

RMXL1
RNA binding motif protein, X-linked-like-1

1

0

High-throughput

0.232

Low

1340188

CCD97
Coiled-coil domain-containing protein 97

1

0

High-throughput

0.232

Low

1340193

RPP25
Ribonuclease P protein subunit p25

1

0

High-throughput

0.232

Low

1340198

F117A
Protein FAM117A

1

0

High-throughput

0.232

Low

1340201

ESF1
ESF1 homolog

1

0

High-throughput

0.232

Low

1340207

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025