HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 998
+	Hs
		153901 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		EPHB1_HUMAN (32-991): 0: 1181: 57.28
+	Hs
		1049958 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1072546 LNX2_HUMAN (4-348): 1.22e-27: 115: 14.33		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1021499 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1020163 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		665600 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		872639 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		872638 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		872669 MAGI2_HUMAN (94-316): 5e-10: 63.1: 14.54		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		872433 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		872431 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		665393 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA3_HUMAN (25-990): 0: 1189: 62.01
+	Hs
		665589 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		665228 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		600564 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		EPHA1_HUMAN (10-986): 0: 975: 44.30
+	Hs
		153881 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		674422 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		674412 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		411472 SNX27_HUMAN (12-91): 4.35e-09: 59.7: 37.63		INSR_HUMAN (284-953): 2.01e-145: 470: 24.71
+	Hs
		412128 DLG4_HUMAN (88-235): 4.14e-14: 75.5: 19.36		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45