HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: CP250 (Q9BV73)
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
Gene: CEP250

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000278 - mitotic cell cycle GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 2442
+	Hs
		724994 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CP250_HUMAN (1-2442): 2.19e-172: 592: 100.00
+	Hs
		154949 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CENPE_HUMAN (1-1454): 3.09e-50: 200: 9.53
+	Hs
		155098 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		AKAP9_HUMAN (2-1515): 4.1e-26: 120: 11.62
+	Hs
		724839 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Hs
		1068617 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Hs
		724687 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43
+	Hs
		725097 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43
+	Rn
		361106 MYH6_RAT (190-583): 3.4e-15: 81.7: 10.63		MYH6_RAT (772-1881): 6.62e-38: 159: 13.11
+	Hs
		725095 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43
+	Mm
		93570 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		MYH9_MOUSE (8-1045): 1.57e-34: 148: 15.73
+	Hs
		502901 MYH6_HUMAN (243-632): 9.68e-15: 80.2: 14.50		MYH3_HUMAN (2-844): 3.25e-33: 143: 11.40
+	Mm
		93578 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		PLEC_MOUSE (2-991): 1.82e-31: 138: 12.27
+	Hs
		1268126 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		724943 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		148460 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		1268060 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		148466 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148461 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		149126 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55