Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: SPC25 (Q9HBM1)
Kinetochore protein Spc25 (hSpc25)
Gene: SPC25

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.755

The method score is based on:

Property Details
Experiments 26186194, 28514442, 14699129, 33961781, 24981860, 34079125, 20360068, 25416956
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, mammalian protein protein interaction trap
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0007052 - mitotic spindle organization
GO:0007059 - chromosome segregation
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 642
Hs

1 224
+ Xl
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024