HitPredict

Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: NRP2 (O60462)
Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2)
Gene: NRP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 25315821
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~CUB, CUB~F5_F8_type_C, F5_F8_type_C~F5_F8_type_C, MAM~MAM
Common GO terms GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002116 - semaphorin receptor complex
GO:0003148 - outflow tract septum morphogenesis
GO:0005021 - vascular endothelial growth factor receptor activity
and 27 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 923
Hs

1 931
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024