HitPredict

Interactor 1: SH21B (O14796)
SH2 domain-containing protein 1B (EWS/FLI1-activated transcript 2) (EAT-2)
Gene: SH2D1B

Interactor 2: PECA1 (P16284)
Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
Gene: PECAM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	23322602
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Hs			1 738
+	Hs
		411985 FYN_HUMAN (3-125): 5.83e-35: 128: 22.48		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		557440 CSK_HUMAN (3-131): 2.76e-35: 127: 23.26		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		411584 LCK_HUMAN (3-127): 1.87e-34: 126: 25.19		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		433242 YES_HUMAN (3-125): 1.4e-34: 126: 23.26		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		442774 HCK_HUMAN (3-125): 2.65e-34: 126: 25.58		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		557441 ABL2_HUMAN (5-131): 3.02e-34: 126: 25.00		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		522751 SRC_HUMAN (3-125): 2.31e-33: 123: 25.58		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		433561 LYN_HUMAN (3-125): 4.15e-33: 122: 23.26		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		434019 LYN_HUMAN (3-125): 4.15e-33: 122: 23.26		ROBO2_HUMAN (11-737): 1.39e-82: 288: 12.20
+	Hs
		433804 LYN_HUMAN (3-125): 4.15e-33: 122: 23.26		SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69
+	Mm
		639452 LYN_MOUSE (3-125): 3.75e-33: 122: 24.03		FCRL5_MOUSE (230-631): 2.04e-45: 173: 17.99
+	Hs
		243129 SH21A_HUMAN (6-113): 2.35e-38: 127: 44.44		CD22_HUMAN (282-633): 8.62e-41: 162: 15.93
+	Hs
		433569 LYN_HUMAN (3-125): 4.15e-33: 122: 23.26		CD22_HUMAN (282-633): 8.62e-41: 162: 15.93
+	Hs
		297881 FYN_HUMAN (3-125): 5.83e-35: 128: 22.48		NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71
+	Hs
		297880 ABL1_HUMAN (5-131): 2.58e-34: 127: 25.78		NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71
+	Hs
		155860 SH21B_HUMAN (1-132): 1.12e-39: 131: 100.00		ROBO1_HUMAN (405-725): 5.45e-33: 139: 11.87
+	Hs
		433742 LYN_HUMAN (3-125): 4.15e-33: 122: 23.26		PTK7_HUMAN (8-235): 3.28e-27: 120: 12.45
+	Hs
		176379 SHIP2_HUMAN (5-102): 1.32e-36: 133: 42.86		VCAM1_HUMAN (28-407): 7.14e-17: 86.9: 19.75
+	Hs
		433249 YES_HUMAN (3-125): 1.4e-34: 126: 23.26		VCAM1_HUMAN (28-407): 7.14e-17: 86.9: 19.75
+	Hs
		255429 LCK_HUMAN (3-127): 1.87e-34: 126: 25.19		OBSL1_HUMAN (72-603): 1.4e-14: 80.3: 15.01