HitPredict

Interactor 1: RPC1 (O14802)
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160)
Gene: POLR3A

Interactor 2: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24981860
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb1_1, RNA_pol_Rpb1_1~RNA_pol_Rpb1_2, RNA_pol_Rpb1_1~RNA_pol_Rpb1_3, RNA_pol_Rpb1_1~RNA_pol_Rpb1_5, RNA_pol_Rpb1_2~RNA_pol_Rpb1_2, RNA_pol_Rpb1_2~RNA_pol_Rpb1_3, RNA_pol_Rpb1_2~RNA_pol_Rpb1_4, RNA_pol_Rpb1_2~RNA_pol_Rpb1_5, RNA_pol_Rpb1_3~RNA_pol_Rpb1_4, RNA_pol_Rpb1_3~RNA_pol_Rpb1_5, RNA_pol_Rpb1_4~RNA_pol_Rpb1_5, RNA_pol_Rpb1_5~RNA_pol_Rpb1_5
Common GO terms GO:0000287 - magnesium ion binding
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1390
Hs

1 1970
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Zm
+ Sc
+ Hv
+ At
+ Hp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024