HitPredict

Interactor 1: ZNT4 (O14863)
Probable proton-coupled zinc antiporter SLC30A4 (Solute carrier family 30 member 4) (Zinc transporter 4) (ZnT-4)
Gene: SLC30A4

Interactor 2: ZNT3 (Q99726)
Probable proton-coupled zinc antiporter SLC30A3 (Solute carrier family 30 member 3) (Zinc transporter 3) (ZnT-3)
Gene: SLC30A3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.798

The method score is based on:

Property Details
Experiments 26728129, 25657003
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_efflux~Cation_efflux
Common GO terms GO:0005385 - zinc ion transmembrane transporter activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome
GO:0005886 - plasma membrane
and 6 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 429
Hs

1 388
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024