HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21642987
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 490 Hs			1 372
+	Hs
		157394 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		157426 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		157433 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		157469 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		453096 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		161943 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		456208 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		157451 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		157449 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		456243 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		456279 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		456228 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		456227 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		174568 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		175106 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87
+	Hs
		161904 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		174624 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Sc
		376753 CDC27_YEAST (28-320): 1.5e-47: 177: 15.05		PABP_YEAST (4-189): 6.12e-39: 147: 24.47
+	Hs
		174877 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		174849 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56