HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: IFIT5 (Q13325)
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58)
Gene: IFIT5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 21163940, 21642987
Identification Methods two hybrid, affinity chromatography technology, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TPR_10~TPR_12, TPR_12~TPR_12, TPR_12~TPR_8, TPR_10~TPR_7, TPR_12~TPR_7, TPR_7~TPR_8, TPR_2~TPR_8, TPR_8~TPR_8
Common GO terms GO:0005829 - cytosol
GO:0051607 - defense response to virus
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 490
Hs

1 482
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Last updated: 15 Jul 2024