Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: TNIP2 (Q8NFZ5)
TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
Gene: TNIP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 30561431, 21784860
Identification Methods affinity chromatography technology, virotrap
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0019901 - protein kinase binding
GO:0034138 - toll-like receptor 3 signaling pathway
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 756
Hs

1 429
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024