Interactor 1: CHK1 (O14757)
Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)
Gene: CHEK1
Interactor 2: MPIP2 (P30305)
M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)
Gene: CDC25B
Species: Homo sapiens
Source: dip
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9278511 |
| Identification Methods | enzymatic study, pull down, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Rhodanese |
| Common GO terms | GO:0000086 - G2/M transition of mitotic cell cycle GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome and 2 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
