HitPredict

Interactor 1: AT2A1 (O14983)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A1

Interactor 2: SETB1 (Q15047)
Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1)
Gene: SETDB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 1291
+	Hs
		163819 AT2A1_HUMAN (1-1001): 0: 977: 100.00		EZH2_HUMAN (1026-1272): 1.18e-48: 188: 13.13
+	Mm
		223165 AT2A2_MOUSE (1-998): 0: 952: 83.97		Q6AXH7_MOUSE (1026-1272): 1.64e-48: 188: 13.13
+	Hs
		561587 AT2A2_HUMAN (1-1000): 0: 950: 83.40		EZH2_HUMAN (1026-1272): 1.18e-48: 188: 13.13
+	Mm
		1149782 AT1A1_MOUSE (2-998): 0: 805: 26.58		Q6AXH7_MOUSE (1026-1272): 1.64e-48: 188: 13.13
+	Hs
		393221 AT1A1_HUMAN (2-998): 0: 803: 26.10		EZH2_HUMAN (1026-1272): 1.18e-48: 188: 13.13
+	Dm
		611067 ATC1_DROME (1-990): 0: 907: 71.82		SETB1_DROME (839-937): 1.86e-11: 71.1: 7.62