HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2390 Hs			1 244
+	Hs
		852438 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RND2_HUMAN (20-244): 3.9e-103: 300: 64.00
+	Hs
		164556 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48
+	Hs
		164648 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RND1_HUMAN (1-244): 1.22e-90: 268: 58.20
+	Hs
		436258 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48
+	Hs
		164598 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84
+	Hs
		164590 SPTN2_HUMAN (1-2390): 0: 715: 100.00		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		893910 SPTB2_HUMAN (3-2390): 0: 712: 61.09		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		901127 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RND3_HUMAN (1-244): 1.15e-81: 246: 100.00
+	Hs
		164599 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Hs
		164593 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27
+	Hs
		164589 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		545327 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89
+	Hs
		900386 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27
+	Hs
		164602 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47
+	Hs
		892322 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		120207 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18
+	Hs
		120393 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18
+	Hs
		164667 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21
+	Hs
		164564 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02
+	Hs
		564483 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02