HitPredict

Interactor 1: SC16A (O15027)
Protein transport protein Sec16A (SEC16 homolog A) (p250)
Gene: SEC16A

Interactor 2: SC24C (P53992)
Protein transport protein Sec24C (SEC24-related protein C)
Gene: SEC24C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 30596474
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0012507 - ER to Golgi transport vesicle membrane GO:0070971 - endoplasmic reticulum exit site
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2357 Hs			1 1094
+	Hs
		164729 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24A_HUMAN (4-1091): 0: 683: 25.43
+	Hs
		164730 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24B_HUMAN (7-1091): 0: 681: 24.22
+	Hs
		164902 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC23B_HUMAN (366-1087): 0: 612: 16.81
+	Hs
		164901 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC23A_HUMAN (366-1087): 0: 607: 16.69
+	Hs
		99722 SC16A_HUMAN (1-2357): 0: 820: 100.00		F5H365_HUMAN (366-1087): 0: 581: 15.94
+	Hs
		302269 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC24C_HUMAN (1-1094): 0: 935: 100.00
+	Hs
		164725 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24D_HUMAN (2-205): 2.27e-12: 73.6: 14.98
+	Sc
		774421 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SEC24_YEAST (186-1091): 0: 632: 24.76
+	Sc
		817592 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SFB2_YEAST (303-1091): 0: 622: 25.80
+	Sc
		755402 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SFB3_YEAST (232-1093): 0: 597: 23.85
+	Ce
		712430 SC161_CAEEL (1432-2256): 2.55e-38: 160: 20.26		Q23368_CAEEL (69-1090): 0: 594: 22.99
+	Sc
		546759 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SEC23_YEAST (368-1087): 1.85e-177: 540: 16.07
+	Sc
		758535 SEC31_YEAST (5-336): 7.22e-09: 63.4: 12.47		SEC24_YEAST (186-1091): 0: 632: 24.76
+	Hs
		302290 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC23B_HUMAN (366-1087): 0: 612: 16.81
+	Hs
		867101 SC24C_HUMAN (716-1040): 9.25e-09: 63.3: 17.02		SC23B_HUMAN (366-1087): 0: 612: 16.81
+	Hs
		302289 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC23A_HUMAN (366-1087): 0: 607: 16.69
+	Hs
		867100 SC24C_HUMAN (716-1040): 9.25e-09: 63.3: 17.02		SC23A_HUMAN (366-1087): 0: 607: 16.69
+	Sc
		546735 SEC31_YEAST (5-336): 7.22e-09: 63.4: 12.47		SEC23_YEAST (368-1087): 1.85e-177: 540: 16.07
+	Hs
		297843 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC24D_HUMAN (2-205): 2.27e-12: 73.6: 14.98