Protein: NC2A
Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)

Gene: NC2A, DRAP1
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q14919

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001046 - core promoter sequence-specific DNA binding
GO:0001091 - RNA polymerase II general transcription initiation factor binding
GO:0005634 - nucleus
GO:0006366 - transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

966144

NC2B
Protein Dr1

14

20

Small-scale

0.983

High

1060236

DPOE3
DNA polymerase epsilon subunit 3

5

20

High-throughput

0.937

High

589861

TBP
TATA-box-binding protein

4

2

Small-scale

0.886

High

627432

NFYB
Nuclear transcription factor Y subunit beta

2

20

High-throughput

0.834

High

1060219

NC2A
Dr1-associated corepressor

2

5

High-throughput

0.826

High

1060221

TAF9
Transcription initiation factor TFIID subunit 9

6

4

High-throughput

0.741

High

1060233

TAF9B
Transcription initiation factor TFIID subunit 9B

4

4

High-throughput

0.705

High

638288

RBTN2
Rhombotin-2

4

1

High-throughput

0.700

High

959932

TF2B
Transcription initiation factor IIB

3

2

High-throughput

0.675

High

132862

SDCB1
Syntenin-1

3

1

High-throughput

0.671

High

1060222

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.665

High

1060231

H2B1N
Histone H2B type 1-N

1

3

High-throughput

0.665

High

1060227

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

4

1

High-throughput

0.623

High

702057

RL9
Large ribosomal subunit protein uL6

2

0

High-throughput

0.580

High

1060229

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

942667

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.569

High

270786

FOXH1
Forkhead box protein H1

1

11

Small-scale

0.561

High

1060226

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.553

High

209054

NCK2
Cytoplasmic protein NCK2

1

0

High-throughput

0.549

High

964182

FOXK2
Forkhead box protein K2

1

9

High-throughput

0.536

High

1060242

FOXD3
Forkhead box protein D3

1

10

High-throughput

0.536

High

378692

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.518

High

790976

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

0

High-throughput

0.518

High

1060237

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.513

High

1060225

LNX2
Ligand of Numb protein X 2

1

1

High-throughput

0.512

High

1060238

DJB11
DnaJ homolog subfamily B member 11

1

4

High-throughput

0.508

High

1060243

TTF2
Transcription termination factor 2

1

5

Small-scale

0.508

High

1060230

FEZ1
Fasciculation and elongation protein zeta-1

1

1

Small-scale

0.481

High

1060244

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

168793

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

2

Small-scale

0.479

High

294837

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

381989

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.479

High

453366

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.479

High

569736

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

1060220

SMAD2
Mothers against decapentaplegic homolog 2

1

2

High-throughput

0.479

High

1060240

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1060232

PKHF2
Pleckstrin homology domain-containing family F member 2

1

2

High-throughput

0.464

High

741051

ZEB1
Zinc finger E-box-binding homeobox 1

1

0

Small-scale

0.460

High

501053

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.458

High

590930

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

394723

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.457

High

1060241

FEZ2
Fasciculation and elongation protein zeta-2

1

1

Small-scale

0.439

High

988888

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

807726

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.437

High

897730

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.437

High

1060223

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

717835

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

1060224

Q8N381
Phosphoinositide-3-kinase, regulatory subunit 3

1

1

High-throughput

0.417

High

1060235

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1060239

MO4L1
Mortality factor 4-like protein 1

2

0

High-throughput

0.316

High

947939

RT11
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.279

Low

1060228

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.265

Low

489963

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

High-throughput

0.249

Low

951564

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

1060234

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024