Protein: FOSL1
Fos-related antigen 1 (FRA-1)

Gene: FOSL1
Organism: Homo sapiens
Interactions: 94
UniProt ID: P15407

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001701 - in utero embryonic development
GO:0002224 - toll-like receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

583986

JUNB
Transcription factor JunB

7

20

Small-scale

0.962

High

429242

JUN
Transcription factor Jun

7

20

Small-scale

0.959

High

584012

CREB5
Cyclic AMP-responsive element-binding protein 5

4

19

High-throughput

0.909

High

583987

JUND
Transcription factor JunD

4

20

Small-scale

0.881

High

583426

ATF2
Cyclic AMP-dependent transcription factor ATF-2

3

19

High-throughput

0.847

High

584047

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

2

19

High-throughput

0.783

High

583988

ATF7
Cyclic AMP-dependent transcription factor ATF-7

2

19

High-throughput

0.776

High

583992

ATF4
Cyclic AMP-dependent transcription factor ATF-4

2

14

Small-scale

0.768

High

584005

CEBPA
CCAAT/enhancer-binding protein alpha

2

19

High-throughput

0.768

High

583994

USF1
Upstream stimulatory factor 1

5

20

Small-scale

0.729

High

584054

NDK7
Nucleoside diphosphate kinase homolog 7

4

3

High-throughput

0.703

High

583985

CREB1
Cyclic AMP-responsive element-binding protein 1

1

15

High-throughput

0.691

High

584048

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

3

10

High-throughput

0.667

High

282156

MAF
Transcription factor Maf

1

20

High-throughput

0.647

High

583991

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

19

High-throughput

0.647

High

584007

CEBPG
CCAAT/enhancer-binding protein gamma

1

20

High-throughput

0.647

High

584025

CEBPE
CCAAT/enhancer-binding protein epsilon

1

20

High-throughput

0.647

High

584055

MAFB
Transcription factor MafB

1

20

High-throughput

0.647

High

343730

LDOC1
Protein LDOC1

2

1

High-throughput

0.640

High

583989

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.618

High

584018

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

1

High-throughput

0.606

High

343669

GGPPS
Geranylgeranyl pyrophosphate synthase

2

1

High-throughput

0.601

High

584016

FP100
Fanconi anemia core complex-associated protein 100

2

1

High-throughput

0.601

High

584026

DNMBP
Dynamin-binding protein

2

1

High-throughput

0.601

High

584014

EP300
Histone acetyltransferase p300

2

19

Small-scale

0.595

High

166490

BACH1
Transcription regulator protein BACH1

1

20

High-throughput

0.575

High

584039

GCC1
GRIP and coiled-coil domain-containing protein 1

2

4

High-throughput

0.553

High

584040

CC120
Coiled-coil domain-containing protein 120

2

1

High-throughput

0.553

High

584042

KIFC3
Kinesin-like protein KIFC3

2

4

High-throughput

0.553

High

583997

SYVC
Valine--tRNA ligase

2

7

High-throughput

0.549

High

180691

TIF1A
Transcription intermediary factor 1-alpha

1

15

High-throughput

0.541

High

584006

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.541

High

584008

ATX1
Ataxin-1

1

4

High-throughput

0.541

High

584049

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

5

High-throughput

0.541

High

340291

YETS4
YEATS domain-containing protein 4

1

4

High-throughput

0.536

High

371071

MYC
Myc proto-oncogene protein

1

16

High-throughput

0.536

High

583999

TEAD1
Transcriptional enhancer factor TEF-1

1

1

Small-scale

0.536

High

584000

EF1D
Elongation factor 1-delta

1

8

High-throughput

0.536

High

584020

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.536

High

584028

FBX11
F-box only protein 11

1

3

High-throughput

0.536

High

584033

STK40
Serine/threonine-protein kinase 40

1

18

High-throughput

0.536

High

584035

COP1
E3 ubiquitin-protein ligase COP1

1

8

High-throughput

0.536

High

584041

TRIB1
Tribbles homolog 1

1

15

High-throughput

0.536

High

584044

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

2

High-throughput

0.536

High

374379

RASH
GTPase HRas

1

5

High-throughput

0.515

High

583995

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.515

High

583998

CLAT
Choline O-acetyltransferase

1

1

High-throughput

0.515

High

584009

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.515

High

584021

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

1

High-throughput

0.515

High

584053

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

584043

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.513

High

362146

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.501

High

584002

DDIT3
DNA damage-inducible transcript 3 protein

1

13

High-throughput

0.501

High

584013

ERCC6
DNA excision repair protein ERCC-6

1

9

High-throughput

0.501

High

584051

DNM3L
DNA

1

10

Small-scale

0.501

High

584045

PARVG
Gamma-parvin

1

1

High-throughput

0.494

High

229943

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

8

High-throughput

0.489

High

248667

PEPL
Periplakin

1

1

High-throughput

0.489

High

584023

RABE1
Rab GTPase-binding effector protein 1

1

2

High-throughput

0.489

High

584027

CNTRL
Centriolin

1

2

High-throughput

0.489

High

584036

LRC20
Leucine-rich repeat-containing protein 20

1

3

High-throughput

0.489

High

584050

HOOK1
Protein Hook homolog 1

1

4

High-throughput

0.489

High

128752

MEN1
Menin

1

6

High-throughput

0.479

High

259381

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.479

High

583990

PRS6A
26S proteasome regulatory subunit 6A

1

4

Small-scale

0.479

High

583993

IL11
Interleukin-11

1

1

Small-scale

0.479

High

584001

ELF1
ETS-related transcription factor Elf-1

1

9

Small-scale

0.479

High

584003

NKX21
Homeobox protein Nkx-2.1

1

14

High-throughput

0.479

High

584011

H4
Histone H4

1

10

High-throughput

0.479

High

584017

TRAF3
TNF receptor-associated factor 3

1

6

Small-scale

0.479

High

584019

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

584038

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

584034

KCNRG
Potassium channel regulatory protein

1

2

High-throughput

0.470

High

245859

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

301328

WFS1
Wolframin

1

1

High-throughput

0.470

High

442221

GELS
Gelsolin

1

3

High-throughput

0.470

High

583996

XPA
DNA repair protein complementing XP-A cells

1

0

Small-scale

0.458

High

584030

TCAM1
TIR domain-containing adapter molecule 1

1

0

Small-scale

0.458

High

225468

CYH3
Cytohesin-3

1

7

High-throughput

0.445

High

274089

ANR17
Ankyrin repeat domain-containing protein 17

1

8

High-throughput

0.445

High

584010

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.445

High

584029

MIB1
E3 ubiquitin-protein ligase MIB1

1

7

High-throughput

0.445

High

584031

P3H2
Prolyl 3-hydroxylase 2

1

1

High-throughput

0.445

High

584052

CP131
Centrosomal protein of 131 kDa

1

3

High-throughput

0.445

High

399262

MMP1
Interstitial collagenase

1

6

Small-scale

0.437

High

584022

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.426

High

584037

SC65
Endoplasmic reticulum protein SC65

1

1

High-throughput

0.407

High

584056

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

1

High-throughput

0.407

High

584046

WFDC1
WAP four-disulfide core domain protein 1

1

0

High-throughput

0.282

High

561103

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.279

Low

584015

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

584004

GSH0
Glutamate--cysteine ligase regulatory subunit

1

0

High-throughput

0.232

Low

584024

PI5PA
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

1

0

High-throughput

0.232

Low

584032

M21D2
Nucleotidyltransferase MB21D2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025