Protein: SPB5
Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5)

Gene: SPB5, SERPINB5
Organism: Homo sapiens
Interactions: 141
UniProt ID: P36952

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002009 - morphogenesis of an epithelium
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

738826

TEST
Testisin

1

17

Small-scale

0.756

High

738730

MK09
Mitogen-activated protein kinase 9

3

4

High-throughput

0.667

High

738756

PLSI
Plastin-1

3

2

High-throughput

0.667

High

738806

EIF2A
Eukaryotic translation initiation factor 2A

3

5

High-throughput

0.667

High

738745

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

3

0

High-throughput

0.638

High

738807

NAA50
N-alpha-acetyltransferase 50

3

0

High-throughput

0.638

High

738760

STK11
Serine/threonine-protein kinase STK11

2

4

High-throughput

0.633

High

738729

GDF5
Growth/differentiation factor 5

2

4

High-throughput

0.628

High

738775

KHDC4
KH homology domain-containing protein 4

2

3

High-throughput

0.628

High

738798

CDK15
Cyclin-dependent kinase 15

2

8

High-throughput

0.628

High

738751

HDAC1
Histone deacetylase 1

2

1

Small-scale

0.625

High

427053

CATD
Cathepsin D

1

1

High-throughput

0.618

High

667923

SPB3
Serpin B3

1

5

High-throughput

0.618

High

738769

MYOME
Myomegalin

2

6

High-throughput

0.611

High

738774

HDGR2
Hepatoma-derived growth factor-related protein 2

2

3

High-throughput

0.611

High

738821

DD19B
ATP-dependent RNA helicase DDX19B

2

9

High-throughput

0.611

High

396446

ALDH2
Aldehyde dehydrogenase, mitochondrial

3

1

High-throughput

0.609

High

738755

GPR18
N-arachidonyl glycine receptor

3

12

High-throughput

0.609

High

738758

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

8

High-throughput

0.609

High

738800

VRK1
Serine/threonine-protein kinase VRK1

3

1

High-throughput

0.609

High

738803

RBM24
RNA-binding protein 24

3

3

High-throughput

0.609

High

738784

CCYL1
Cyclin-Y-like protein 1

2

2

High-throughput

0.574

High

738785

FRMD1
FERM domain-containing protein 1

2

3

High-throughput

0.574

High

738790

IL31R
Interleukin-31 receptor subunit alpha

2

1

High-throughput

0.574

High

738809

ACAD9
Complex I assembly factor ACAD9, mitochondrial

2

3

High-throughput

0.574

High

738814

TB22B
TBC1 domain family member 22B

2

7

High-throughput

0.574

High

738823

FCF1
rRNA-processing protein FCF1 homolog

2

4

High-throughput

0.574

High

738737

RHOA
Transforming protein RhoA

2

3

High-throughput

0.558

High

738761

RB11B
Ras-related protein Rab-11B

2

4

High-throughput

0.558

High

738766

SGO2
Shugoshin 2

2

1

High-throughput

0.558

High

738773

DDX46
Probable ATP-dependent RNA helicase DDX46

2

2

High-throughput

0.558

High

738794

FBX32
F-box only protein 32

1

1

Small-scale

0.552

High

597481

GSTM3
Glutathione S-transferase Mu 3

1

0

Small-scale

0.549

High

207022

XRCC3
DNA repair protein XRCC3

1

1

High-throughput

0.541

High

275546

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

12

High-throughput

0.541

High

349934

RASK
GTPase KRas

1

6

High-throughput

0.541

High

369104

ESR1
Estrogen receptor

1

12

High-throughput

0.541

High

681699

AKT1
RAC-alpha serine/threonine-protein kinase

1

7

High-throughput

0.541

High

738750

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.541

High

738757

CASP8
Caspase-8

1

8

High-throughput

0.541

High

338047

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.536

High

365161

FRIH
Ferritin heavy chain

1

5

High-throughput

0.536

High

565888

AATC
Aspartate aminotransferase, cytoplasmic

1

8

High-throughput

0.536

High

738734

MMP14
Matrix metalloproteinase-14

1

3

High-throughput

0.536

High

738748

HSF2
Heat shock factor protein 2

1

1

High-throughput

0.536

High

738762

ZYX
Zyxin

1

2

High-throughput

0.536

High

738770

JADE1
Protein Jade-1

1

1

High-throughput

0.536

High

738780

TEX14
Inactive serine/threonine-protein kinase TEX14

1

14

High-throughput

0.536

High

738793

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.536

High

738795

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

4

High-throughput

0.536

High

738799

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.536

High

738801

TREX2
Three prime repair exonuclease 2

1

2

High-throughput

0.536

High

738804

SRRT
Serrate RNA effector molecule homolog

1

5

High-throughput

0.536

High

738820

HDAC9
Histone deacetylase 9

1

4

High-throughput

0.536

High

738822

SSUH2
Protein SSUH2 homolog

1

8

High-throughput

0.536

High

436017

CO1A2
Collagen alpha-2(I) chain

1

2

Small-scale

0.527

High

397817

ISG15
Ubiquitin-like protein ISG15

1

1

High-throughput

0.515

High

234912

SNX3
Sorting nexin-3

1

0

High-throughput

0.513

High

738802

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.513

High

738818

FBX3
F-box only protein 3

1

0

High-throughput

0.513

High

738825

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

3

Small-scale

0.501

High

738786

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.493

High

239827

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.489

High

303662

OR2A4
Olfactory receptor 2A4

1

13

High-throughput

0.489

High

738733

PTSS1
Phosphatidylserine synthase 1

1

2

High-throughput

0.489

High

738735

STX17
Syntaxin-17

1

10

High-throughput

0.489

High

738736

DSCR6
Protein ripply3

1

7

High-throughput

0.489

High

738743

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

9

High-throughput

0.489

High

738746

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

3

High-throughput

0.489

High

738765

FNDC1
Fibronectin type III domain-containing protein 1

1

5

High-throughput

0.489

High

738767

LRC10
Leucine-rich repeat-containing protein 10

1

4

High-throughput

0.489

High

738776

ZC3C1
Zinc finger C3HC-type protein 1

1

5

High-throughput

0.489

High

738789

O13C3
Olfactory receptor 13C3

1

4

High-throughput

0.489

High

738796

RM38
Large ribosomal subunit protein mL38

1

3

High-throughput

0.489

High

738797

F227B
Protein FAM227B

1

3

High-throughput

0.489

High

738810

COE2
Transcription factor COE2

1

5

High-throughput

0.489

High

738815

KLH11
Kelch-like protein 11

1

6

High-throughput

0.489

High

431604

HS90A
Heat shock protein HSP 90-alpha

1

6

Small-scale

0.481

High

437953

HS90B
Heat shock protein HSP 90-beta

1

6

Small-scale

0.481

High

501768

BIP
Endoplasmic reticulum chaperone BiP

1

11

Small-scale

0.481

High

673662

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

2

Small-scale

0.481

High

738739

EF1A1
Elongation factor 1-alpha 1

1

3

Small-scale

0.481

High

738749

GOGA4
Golgin subfamily A member 4

1

3

Small-scale

0.481

High

157825

IRF6
Interferon regulatory factor 6

1

1

Small-scale

0.479

High

377147

GCR
Glucocorticoid receptor

1

12

High-throughput

0.479

High

428562

INVO
Involucrin

1

1

High-throughput

0.479

High

503569

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

584888

RO52
E3 ubiquitin-protein ligase TRIM21

1

3

Small-scale

0.479

High

683047

CASPE
Caspase-14

1

8

High-throughput

0.479

High

683878

1433S
14-3-3 protein sigma

1

5

High-throughput

0.479

High

738731

LEG7
Galectin-7

1

5

High-throughput

0.479

High

738732

SOX2
Transcription factor SOX-2

1

13

High-throughput

0.479

High

738744

VIGLN
Vigilin

1

4

High-throughput

0.479

High

738752

PKP1
Plakophilin-1

1

4

High-throughput

0.479

High

738753

BLMH
Bleomycin hydrolase

1

2

High-throughput

0.479

High

738813

FBX6
F-box only protein 6

1

7

High-throughput

0.479

High

738816

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

589801

TBP
TATA-box-binding protein

1

0

Small-scale

0.460

High

738728

MDHC
Malate dehydrogenase, cytoplasmic

1

0

Small-scale

0.460

High

738740

GSTO1
Glutathione S-transferase omega-1

1

0

Small-scale

0.460

High

738741

MT1H
Metallothionein-1H

1

0

Small-scale

0.460

High

738742

BASP1
Brain acid soluble protein 1

1

0

Small-scale

0.460

High

738764

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

0

Small-scale

0.460

High

48098

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

0

High-throughput

0.458

High

213804

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

588848

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.458

High

738738

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.458

High

738808

RANB3
Ran-binding protein 3

1

0

High-throughput

0.458

High

643438

PTBP1
Polypyrimidine tract-binding protein 1

1

1

High-throughput

0.439

High

244035

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

738781

CUL9
Cullin-9

1

4

High-throughput

0.437

High

738787

NKAI3
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3

1

1

High-throughput

0.437

High

738788

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.437

High

738792

POF1B
Protein POF1B

1

1

High-throughput

0.437

High

738805

FACD2
Fanconi anemia group D2 protein

1

14

High-throughput

0.437

High

738811

UD110
UDP-glucuronosyltransferase 1A10

1

3

High-throughput

0.437

High

738812

RAB9B
Ras-related protein Rab-9B

1

6

High-throughput

0.437

High

738817

CALL5
Calmodulin-like protein 5

1

2

High-throughput

0.437

High

47335

A0A6Q8PFP9
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein

1

1

High-throughput

0.407

High

63222

RP1BL
Ras-related protein Rap-1b-like protein

1

8

High-throughput

0.407

High

738772

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

2

High-throughput

0.407

High

738782

SLX4
Structure-specific endonuclease subunit SLX4

1

6

High-throughput

0.407

High

738779

LACC1
Purine nucleoside phosphorylase LACC1

4

0

Small-scale

0.360

High

738763

SYT16
Synaptotagmin-16

2

0

High-throughput

0.328

High

738777

GPBP1
Vasculin

2

0

High-throughput

0.328

High

738783

CCD82
Coiled-coil domain-containing protein 82

2

0

High-throughput

0.328

High

738791

CPLX3
Complexin-3

2

0

High-throughput

0.328

High

738819

FBXL4
F-box/LRR-repeat protein 4

2

0

High-throughput

0.328

High

738824

KIF3A
Kinesin-like protein KIF3A

2

0

High-throughput

0.328

High

256472

ZC11A
Zinc finger CCCH domain-containing protein 11A

2

0

High-throughput

0.318

High

307775

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

2

0

High-throughput

0.318

High

738754

PEBB
Core-binding factor subunit beta

2

0

High-throughput

0.318

High

267484

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

0

Small-scale

0.288

High

738778

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.282

High

738768

CX066
Uncharacterized protein CXorf66

1

0

High-throughput

0.279

Low

666849

TKT
Transketolase

1

0

Small-scale

0.251

Low

682484

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

Small-scale

0.251

Low

309668

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.249

Low

738747

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.249

Low

738759

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.249

Low

738771

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024