HitPredict

Interactor 1: BACH1 (O14867)
Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303)
Gene: BACH1

Interactor 2: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19011633
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 2440
+	Mm
		1021101 BACH1_MOUSE (1-736): 3.83e-179: 531: 80.27		NCOR1_MOUSE (1-2440): 0: 685: 89.63
+	Hs
		278422 BACH2_HUMAN (1-736): 7.17e-133: 415: 28.95		NCOR1_HUMAN (1-2440): 0: 760: 100.00
+	Hs
		278195 ZBT7A_HUMAN (1-532): 3.68e-60: 214: 13.45		NCOR1_HUMAN (1-2440): 0: 760: 100.00
+	Hs
		1419366 BACH2_HUMAN (1-736): 7.17e-133: 415: 28.95		NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91
+	Hs
		278260 BCL6_HUMAN (16-127): 3.16e-13: 75.1: 38.05		NCOR1_HUMAN (1-2440): 0: 760: 100.00
+	Hs
		278359 NF2L2_HUMAN (524-620): 7.74e-13: 73.9: 42.27		NCOR1_HUMAN (1-2440): 0: 760: 100.00
+	Hs
		334600 ZBT7A_HUMAN (1-532): 3.68e-60: 214: 13.45		NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91
+	Hs
		832848 BCL6_HUMAN (16-127): 3.16e-13: 75.1: 38.05		NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91
+	Hs
		1156724 NF2L2_HUMAN (524-620): 7.74e-13: 73.9: 42.27		NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91
+	Hs
		1121558 KEAP1_HUMAN (2-392): 1.17e-62: 222: 16.50		RCOR1_HUMAN (360-717): 6.94e-75: 260: 19.40
+	Hs
		1129793 KLH20_HUMAN (8-365): 5.63e-77: 261: 17.66		MDC1_HUMAN (683-2424): 9.89e-54: 211: 10.66
+	Mm
		1296847 ZBT7C_MOUSE (1-481): 2.27e-64: 227: 11.78		Q8BK32_MOUSE (1-289): 5.82e-68: 233: 91.72
+	Hs
		1335949 ZBT44_HUMAN (18-294): 6.4e-66: 230: 26.96		CIC_HUMAN (540-2042): 2.74e-13: 78.4: 8.58
+	Hs
		334578 ZBT7A_HUMAN (1-532): 3.68e-60: 214: 13.45		CIC_HUMAN (540-2042): 2.74e-13: 78.4: 8.58
+	Hs
		832777 BCL6_HUMAN (16-127): 3.16e-13: 75.1: 38.05		MINT_HUMAN (13-2436): 7.59e-52: 205: 9.42
+	Hs
		1387832 ZBT10_HUMAN (20-127): 3.76e-12: 72: 33.33		CIC_HUMAN (540-2042): 2.74e-13: 78.4: 8.58
+	Hs
		1094508 ZBT17_HUMAN (227-490): 5.74e-12: 71.2: 5.63		CIC_HUMAN (540-2042): 2.74e-13: 78.4: 8.58
+	Hs
		208886 ZBT24_HUMAN (13-125): 6.56e-12: 70.9: 35.40		CIC_HUMAN (540-2042): 2.74e-13: 78.4: 8.58