HitPredict

Interactor 1: NACAD (O15069)
NAC-alpha domain-containing protein 1
Gene: NACAD

Interactor 2: BTF3 (P20290)
Transcription factor BTF3 (Nascent polypeptide-associated complex subunit beta) (NAC-beta) (RNA polymerase B transcription factor 3)
Gene: BTF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 35235311
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NAC~NAC
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005854 - nascent polypeptide-associated complex GO:0015031 - protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1562 Hs			1 206
+	Hs
		166511 NACAD_HUMAN (1-1562): 8.2e-123: 423: 100.00		BT3L4_HUMAN (50-206): 5.07e-67: 204: 81.01
+	Hs
		590906 NACA_HUMAN (1351-1562): 6.2e-30: 121: 60.38		BTF3_HUMAN (1-206): 3.5e-94: 275: 100.00
+	Dm
		1180836 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		Q7KM15_DROME (50-201): 3.3e-57: 179: 63.40
+	Ce
		1090365 NACA_CAEEL (1354-1562): 1.09e-38: 145: 46.89		BTF3_CAEEL (53-204): 4.88e-59: 184: 63.16
+	Hs
		1045198 NACA_HUMAN (1351-1562): 6.2e-30: 121: 60.38		BT3L4_HUMAN (50-206): 5.07e-67: 204: 81.01
+	Dm
		1372034 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		Q9VPR2_DROME (50-205): 6.66e-44: 157: 59.87
+	Dm
		1180829 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		Q7KM15_DROME (50-201): 3.3e-57: 179: 63.40
+	Sc
		756709 NACA_YEAST (1402-1561): 9.08e-38: 141: 37.06		NACB1_YEAST (50-199): 3.71e-48: 156: 36.13
+	Sc
		756680 NACA_YEAST (1402-1561): 9.08e-38: 141: 37.06		NACB2_YEAST (50-172): 2.41e-43: 144: 34.92
+	Dm
		1276591 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		Q9VPR2_DROME (50-205): 6.66e-44: 157: 59.87
+	Dm
		1372155 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		Q9VY34_DROME (50-136): 4.56e-27: 105: 35.63
+	Dm
		71738 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		B3DNI1_DROME (50-136): 1.25e-26: 104: 36.78
+	Dm
		1001360 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		Q0IGS9_DROME (50-136): 2.9e-26: 103: 34.48
+	Dm
		1372156 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		Q9VY63_DROME (50-136): 3.25e-26: 103: 36.78
+	Dm
		80856 Q9VPV7_DROME (1230-1562): 7.92e-41: 156: 26.55		B6VQA0_DROME (50-136): 3.35e-26: 102: 34.48
+	Dm
		1276606 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		Q9VY34_DROME (50-136): 4.56e-27: 105: 35.63
+	Dm
		71736 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		B3DNI1_DROME (50-136): 1.25e-26: 104: 36.78
+	Dm
		1001359 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		Q0IGS9_DROME (50-136): 2.9e-26: 103: 34.48
+	Dm
		1215140 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		Q8IR50_DROME (50-136): 3.35e-26: 102: 34.48
+	Dm
		80854 NACA_DROME (1342-1562): 5.89e-30: 121: 45.25		B6VQA0_DROME (50-136): 3.35e-26: 102: 34.48