Protein: NFE2
Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2) (Nuclear factor, erythroid-derived 2 45 kDa subunit) (p45 NF-E2)

Gene: NFE2
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q16621

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1159563

NFE2
Transcription factor NF-E2 45 kDa subunit

3

19

Small-scale

0.845

High

193342

MAFG
Transcription factor MafG

2

19

Small-scale

0.778

High

1159573

NF2L3
Nuclear factor erythroid 2-related factor 3

2

19

High-throughput

0.778

High

605258

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

20

High-throughput

0.647

High

617226

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

8

High-throughput

0.647

High

1126852

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

20

High-throughput

0.647

High

1156662

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

High-throughput

0.647

High

1159570

ZHANG
CREB/ATF bZIP transcription factor

1

6

High-throughput

0.647

High

1159569

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

13

Small-scale

0.643

High

853693

MK08
Mitogen-activated protein kinase 8

1

20

Small-scale

0.586

High

1159567

CBP
CREB-binding protein

1

20

Small-scale

0.578

High

1159572

FBW1A
F-box/WD repeat-containing protein 1A

1

19

High-throughput

0.573

High

944181

SCND1
SCAN domain-containing protein 1

1

1

High-throughput

0.541

High

1159571

ELF5
ETS-related transcription factor Elf-5

1

20

High-throughput

0.541

High

862178

YAP1
Transcriptional coactivator YAP1

1

13

Small-scale

0.527

High

238783

SSX5
Protein SSX5

1

0

High-throughput

0.518

High

424413

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.518

High

442330

GELS
Gelsolin

1

3

High-throughput

0.515

High

1159564

GLE1
mRNA export factor GLE1

1

3

High-throughput

0.515

High

1159565

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

993596

UBC9
SUMO-conjugating enzyme UBC9

1

7

Small-scale

0.501

High

1159568

KAT2B
Histone acetyltransferase KAT2B

1

15

Small-scale

0.501

High

462155

GALT
Galactose-1-phosphate uridylyltransferase

1

0

High-throughput

0.493

High

528263

THIO
Thioredoxin

1

4

High-throughput

0.481

High

861625

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

12

Small-scale

0.481

High

853800

MK09
Mitogen-activated protein kinase 9

1

20

Small-scale

0.479

High

650182

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.470

High

1159566

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.438

High

1159574

Q9Y649
GW128

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025