HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: LRC49 (Q8IUZ0)
Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4)
Gene: LRRC49

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0034451 - centriolar satellite
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2479 Hs			1 686
+	Hs
		166742 CE290_HUMAN (1-2479): 0: 650: 100.00		CEP97_HUMAN (24-184): 1.03e-10: 67: 16.13
+	Mm
		1149154 CE290_MOUSE (1-2451): 0: 628: 87.07		CEP97_MOUSE (27-206): 1.74e-12: 72.7: 16.84
+	Hs
		232887 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232885 GOGB1_HUMAN (3-911): 1.12e-25: 119: 13.23		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232778 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232811 CENPF_HUMAN (1981-2471): 1.41e-10: 69.6: 10.37		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232898 GRDN_HUMAN (1673-2432): 5.52e-10: 67.5: 20.15		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232775 TPR_HUMAN (8-398): 1.3e-09: 66.3: 13.85		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		728512 MYH11_HUMAN (1711-2478): 4.28e-17: 91: 14.71		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		502914 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		PP1R7_HUMAN (12-192): 4.27e-20: 94.3: 23.37
+	Hs
		502869 LAMC1_HUMAN (74-649): 2.52e-12: 75.2: 15.91		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		974133 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		ERBIN_HUMAN (71-443): 9.62e-37: 150: 19.61
+	Hs
		148800 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		SCRIB_HUMAN (4-255): 3.48e-34: 142: 18.51
+	Hs
		518920 TPR_HUMAN (8-398): 1.3e-09: 66.3: 13.85		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		725235 MYH10_HUMAN (1915-2469): 2.86e-09: 65.2: 14.34		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		551759 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		CNTRL_HUMAN (26-183): 5.88e-09: 62: 17.26