Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK
Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.691 |
The method score is based on:
Property | Details |
---|---|
Experiments | 30561431 |
Identification Methods | affinity chromatography technology, virotrap |
Interaction Type | physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | DED~Pkinase |
Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009898 - cytoplasmic side of plasma membrane GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0044877 - protein-containing complex binding and 2 others more... |
Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024