HitPredict

Interactor 1: ZBT7B (O15156)
Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK)
Gene: ZBTB7B

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

The method score is based on:

Property	Details
Experiments	30017585, 22139845
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005654 - nucleoplasm and 5 others more... GO:0006357 - regulation of transcription by RNA polymerase II GO:0010628 - positive regulation of gene expression GO:0032868 - response to insulin GO:0042803 - protein homodimerization activity GO:0042826 - histone deacetylase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	539
Hs

1	551

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024