HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPAC2 (P0DPB6)
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19)
Gene: POLR1D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 25416956, 35271311, 28514442, unassigned1304, 33961781, 16189514
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, mammalian protein protein interaction trap, two hybrid pooling approach
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_L_2
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0005666 - RNA polymerase III complex
GO:0005736 - RNA polymerase I complex
and 1 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 346
Hs

1 133
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Last updated: 15 Jul 2024