HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28813667, 35803934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 1962
+	Mm
		1112701 TIF1A_MOUSE (1-1050): 0: 587: 92.23		TNR6A_MOUSE (1-1962): 0: 835: 89.70
+	Hs
		170512 TIF1A_HUMAN (1-1050): 0: 590: 100.00		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		170483 TIF1A_HUMAN (1-1050): 0: 590: 100.00		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Hs
		164430 TRI66_HUMAN (334-1047): 1.44e-37: 155: 21.67		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		669079 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		170437 TIF1A_HUMAN (1-1050): 0: 590: 100.00		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		170402 TIF1A_HUMAN (1-1050): 0: 590: 100.00		SRCAP_HUMAN (1139-1823): 1.12e-12: 75.9: 10.82
+	Mm
		101463 TRI33_MOUSE (53-1045): 2.62e-142: 457: 46.08		F8VPR5_MOUSE (735-1757): 5.22e-19: 96.7: 10.60
+	Hs
		1350300 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30
+	Dm
		1249014 Q9W378_DROME (7-433): 2.69e-68: 251: 23.21		GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88
+	Mm
		70879 EP300_MOUSE (376-1001): 3.38e-64: 240: 15.94		F8VPR5_MOUSE (735-1757): 5.22e-19: 96.7: 10.60
+	Hs
		1270755 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		668872 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		1170076 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SRCAP_HUMAN (1139-1823): 1.12e-12: 75.9: 10.82
+	Hs
		998940 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		584938 RO52_HUMAN (114-485): 2.09e-64: 227: 12.67		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		62680 TRI64_HUMAN (118-485): 3.11e-58: 209: 12.16		RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30
+	Hs
		669033 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30
+	Hs
		1029691 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		998648 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05