HitPredict

Interactor 1: PGRC2 (O15173)
Membrane-associated progesterone receptor component 2 (Progesterone membrane-binding protein) (Steroid receptor protein DG6)
Gene: PGRMC2

Interactor 2: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005783 - endoplasmic reticulum
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 806
+	Hs
		170802 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		EPHA8_HUMAN (1-771): 0: 593: 20.56
+	Hs
		170856 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59
+	Hs
		170769 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02
+	Hs
		170775 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		RET_HUMAN (453-801): 9.71e-98: 330: 48.63
+	Hs
		170808 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22
+	Hs
		170782 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32
+	Hs
		170797 PGRC2_HUMAN (1-223): 8.54e-88: 260: 100.00		FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31
+	Hs
		123474 PGRC1_HUMAN (77-222): 7.39e-60: 188: 61.64		FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32