HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: ENPL (P14625)
Endoplasmin (EC 3.6.4.-) (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 35575683
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 803
+	Hs
		468315 ANK3_HUMAN (1-596): 4.41e-62: 234: 11.90		HS90B_HUMAN (75-783): 0: 990: 46.26
+	Hs
		461301 DAPK1_HUMAN (11-307): 2.83e-57: 218: 22.26		HS90A_HUMAN (60-783): 0: 983: 45.07
+	Hs
		468611 ANKK1_HUMAN (71-423): 6.45e-49: 188: 15.22		HS90B_HUMAN (75-783): 0: 990: 46.26
+	Hs
		461724 ANKK1_HUMAN (71-423): 6.45e-49: 188: 15.22		HS90A_HUMAN (60-783): 0: 983: 45.07
+	Mm
		59572 A2AM57_MOUSE (111-955): 2.72e-24: 112: 8.53		HS90B_MOUSE (75-783): 0: 991: 45.98
+	Mm
		59637 A2AM57_MOUSE (111-955): 2.72e-24: 112: 8.53		Q71LX8_MOUSE (75-783): 0: 991: 45.98
+	Mm
		313289 INVS_MOUSE (111-955): 3.89e-24: 111: 8.77		HS90B_MOUSE (75-783): 0: 991: 45.98
+	Hs
		295445 PSD10_HUMAN (37-174): 3.01e-09: 60.5: 34.29		HS90A_HUMAN (60-783): 0: 983: 45.07