HitPredict

Interactor 1: SMAD9 (O15198)
Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (Madh6) (SMAD family member 9) (SMAD 9) (Smad9)
Gene: SMAD9

Interactor 2: MED24 (O75448)
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)
Gene: MED24

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27703004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 467 Hs			1 989
+	Hs
		265331 SMAD1_HUMAN (7-467): 0: 641: 80.86		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		265356 SMAD5_HUMAN (4-467): 0: 631: 78.37		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		265317 SMAD3_HUMAN (7-467): 0: 580: 58.19		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		265330 SMAD2_HUMAN (7-467): 0: 565: 53.77		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		167313 SMAD7_HUMAN (34-195): 1.64e-33: 132: 27.59		MED24_HUMAN (1-989): 0: 1590: 100.00