HitPredict

Interactor 1: SMAD9 (O15198)
Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (Madh6) (SMAD family member 9) (SMAD 9) (Smad9)
Gene: SMAD9

Interactor 2: TOB1 (P50616)
Protein Tob1 (Transducer of erbB-2 1)
Gene: TOB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11163184
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 467 Hs			1 345
+	Hs
		841388 SMAD1_HUMAN (7-467): 0: 641: 80.86		TOB1_HUMAN (1-345): 4.62e-165: 465: 100.00
+	Hs
		841398 SMAD5_HUMAN (4-467): 0: 631: 78.37		TOB1_HUMAN (1-345): 4.62e-165: 465: 100.00
+	Hs
		841379 SMAD3_HUMAN (7-467): 0: 580: 58.19		TOB1_HUMAN (1-345): 4.62e-165: 465: 100.00
+	Dr
		1186359 Q8AY15_DANRE (9-467): 0: 583: 58.23		Q7SZP8_DANRE (1-345): 1.19e-153: 436: 74.86
+	Dr
		1186360 Q8AY16_DANRE (9-467): 0: 577: 57.79		Q7SZP8_DANRE (1-345): 1.19e-153: 436: 74.86
+	Dr
		1186362 Q8AY15_DANRE (9-467): 0: 583: 58.23		Q7SZR1_DANRE (1-345): 1.62e-141: 405: 78.74
+	Dr
		1186363 Q8AY16_DANRE (9-467): 0: 577: 57.79		Q7SZR1_DANRE (1-345): 1.62e-141: 405: 78.74
+	Hs
		841384 SMAD4_HUMAN (12-456): 7.46e-162: 470: 34.46		TOB1_HUMAN (1-345): 4.62e-165: 465: 100.00
+	Dm
		60229 MAD_DROME (3-467): 0: 622: 71.83		A4V4L0_DROME (1-313): 2.45e-99: 305: 39.00
+	Mm
		936604 SMAD1_MOUSE (7-467): 0: 643: 80.86		BTG2_MOUSE (1-115): 3.28e-54: 177: 41.88
+	Mm
		978996 SMAD9_MOUSE (1-467): 0: 625: 86.72		BTG2_MOUSE (1-115): 3.28e-54: 177: 41.88