Protein: S27A1
Long-chain fatty acid transport protein 1 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Fatty acid transport protein 1) (FATP-1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 1) (Very long-chain acyl-CoA synthetase) (EC 6.2.1.-)

Gene: S27A1, SLC27A1
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q6PCB7

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0001579 - medium-chain fatty acid transport
GO:0001676 - long-chain fatty acid metabolic process
GO:0004467 - long-chain fatty acid-CoA ligase activity
GO:0005324 - long-chain fatty acid transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1240873

S27A4
Long-chain fatty acid transport protein 4

2

13

High-throughput

0.737

High

828383

PEX19
Peroxisomal biogenesis factor 19

2

2

High-throughput

0.601

High

1213620

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

2

High-throughput

0.601

High

1243646

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

3

4

High-throughput

0.587

High

991348

SUMO1
Small ubiquitin-related modifier 1

1

0

High-throughput

0.546

High

1157628

RPE65
Retinoid isomerohydrolase

1

0

Small-scale

0.537

High

165965

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.536

High

182603

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

349452

TSN15
Tetraspanin-15

1

6

High-throughput

0.536

High

388132

ACHA
Acetylcholine receptor subunit alpha

1

3

High-throughput

0.536

High

549801

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

1

High-throughput

0.536

High

946562

EVA1C
Protein eva-1 homolog C

1

3

High-throughput

0.536

High

1126311

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

5

High-throughput

0.536

High

1203694

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.536

High

1242829

S39A4
Zinc transporter ZIP4

1

4

High-throughput

0.536

High

1243626

CA210
Type III endosome membrane protein TEMP

1

1

High-throughput

0.536

High

1243651

ZDH12
Palmitoyltransferase ZDHHC12

1

3

High-throughput

0.536

High

1243659

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

5

High-throughput

0.536

High

1243665

LPAR2
Lysophosphatidic acid receptor 2

1

3

High-throughput

0.536

High

1243666

ITM2C
Integral membrane protein 2C

1

2

High-throughput

0.536

High

1243650

SAAL1
Protein SAAL1

2

2

High-throughput

0.504

High

469502

SYPH
Synaptophysin

1

1

High-throughput

0.489

High

656005

CAH6
Carbonic anhydrase 6

1

1

High-throughput

0.489

High

1243625

S22A9
Organic anion transporter 7

1

3

High-throughput

0.489

High

1243654

DGAT2
Diacylglycerol O-acyltransferase 2

1

1

Small-scale

0.479

High

208520

PJA2
E3 ubiquitin-protein ligase Praja-2

1

5

High-throughput

0.445

High

211802

ZW10
Centromere/kinetochore protein zw10 homolog

1

1

High-throughput

0.445

High

229734

CALU
Calumenin

1

4

High-throughput

0.445

High

334805

IPO7
Importin-7

1

20

High-throughput

0.445

High

441490

AGAL
Alpha-galactosidase A

1

1

High-throughput

0.445

High

531089

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

2

High-throughput

0.445

High

605721

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.445

High

617312

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

8

High-throughput

0.445

High

627358

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

4

High-throughput

0.445

High

717865

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

8

High-throughput

0.445

High

839296

MTOR
Serine/threonine-protein kinase mTOR

1

3

High-throughput

0.445

High

841197

CNDD3
Condensin-2 complex subunit D3

1

2

High-throughput

0.445

High

890512

RBP2
E3 SUMO-protein ligase RanBP2

1

1

High-throughput

0.445

High

890842

TSC2
Tuberin

1

1

High-throughput

0.445

High

897580

KNTC1
Kinetochore-associated protein 1

1

1

High-throughput

0.445

High

903961

BAP31
B-cell receptor-associated protein 31

1

5

High-throughput

0.445

High

934097

XPO2
Exportin-2

1

20

High-throughput

0.445

High

944502

GEMI4
Gem-associated protein 4

1

2

High-throughput

0.445

High

945255

NU107
Nuclear pore complex protein Nup107

1

2

High-throughput

0.445

High

1034267

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

1

High-throughput

0.445

High

1093527

TRDN
Triadin

1

5

High-throughput

0.445

High

1124980

RCN2
Reticulocalbin-2

1

4

High-throughput

0.445

High

1134240

IMB1
Importin subunit beta-1

1

14

High-throughput

0.445

High

1140436

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.445

High

1153176

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

10

High-throughput

0.445

High

1197797

S39AC
Zinc transporter ZIP12

1

4

High-throughput

0.445

High

1204742

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

6

High-throughput

0.445

High

1211070

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

4

High-throughput

0.445

High

1224738

RN213
E3 ubiquitin-protein ligase RNF213

1

1

High-throughput

0.445

High

1243612

LCLT1
Lysocardiolipin acyltransferase 1

1

2

High-throughput

0.445

High

1243616

DYM
Dymeclin

1

3

High-throughput

0.445

High

1243618

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.445

High

1243619

KAISO
Transcriptional regulator Kaiso

1

1

High-throughput

0.445

High

1243620

NLRX1
NLR family member X1

1

2

High-throughput

0.445

High

1243622

LIPB1
Liprin-beta-1

1

1

High-throughput

0.445

High

1243623

CNDG2
Condensin-2 complex subunit G2

1

2

High-throughput

0.445

High

1243627

EXOC8
Exocyst complex component 8

1

2

High-throughput

0.445

High

1243628

S22AF
Solute carrier family 22 member 15

1

3

High-throughput

0.445

High

1243630

MIGA1
Mitoguardin 1

1

5

High-throughput

0.445

High

1243634

CIP2A
Protein CIP2A

1

3

High-throughput

0.445

High

1243635

NU133
Nuclear pore complex protein Nup133

1

2

High-throughput

0.445

High

1243638

S39A7
Zinc transporter SLC39A7

1

4

High-throughput

0.445

High

1243639

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.445

High

1243641

UBXN4
UBX domain-containing protein 4

1

1

High-throughput

0.445

High

1243642

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.445

High

1243643

NU205
Nuclear pore complex protein Nup205

1

3

High-throughput

0.445

High

1243645

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

5

High-throughput

0.445

High

1243653

IPO9
Importin-9

1

20

High-throughput

0.445

High

1243655

GCP2
Gamma-tubulin complex component 2

1

2

High-throughput

0.445

High

1243656

NDC1
Nucleoporin NDC1

1

1

High-throughput

0.445

High

1243657

LST8
Target of rapamycin complex subunit LST8

1

2

High-throughput

0.445

High

1243658

NUP85
Nuclear pore complex protein Nup85

1

3

High-throughput

0.445

High

1243663

HEAT1
HEAT repeat-containing protein 1

1

2

High-throughput

0.445

High

1243667

AAAS
Aladin

1

3

High-throughput

0.445

High

1243669

FANCI
Fanconi anemia group I protein

1

2

High-throughput

0.445

High

1243671

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

3

High-throughput

0.445

High

1243672

ATX10
Ataxin-10

1

2

High-throughput

0.445

High

1243674

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

2

High-throughput

0.445

High

1243675

DDX20
Probable ATP-dependent RNA helicase DDX20

1

3

High-throughput

0.445

High

106120

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

293871

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

377612

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

1004720

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1243614

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

390624

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.426

High

529972

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

911986

DGKE
Diacylglycerol kinase epsilon

1

0

High-throughput

0.426

High

1091858

ABR
Active breakpoint cluster region-related protein

1

0

High-throughput

0.426

High

1197240

MBRL
Membralin

1

0

High-throughput

0.426

High

1243640

NICA
Nicastrin

1

0

High-throughput

0.426

High

51438

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

11

High-throughput

0.407

High

64766

RIMC1
RAB7A-interacting MON1-CCZ1 complex subunit 1

1

1

High-throughput

0.407

High

67476

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

2

High-throughput

0.407

High

156142

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

2

High-throughput

0.407

High

167096

GEMI2
Gem-associated protein 2

1

1

High-throughput

0.407

High

173711

BTAF1
TATA-binding protein-associated factor 172

1

4

High-throughput

0.407

High

177242

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

2

High-throughput

0.407

High

189194

IPO8
Importin-8

1

20

High-throughput

0.407

High

208057

TTI1
TELO2-interacting protein 1 homolog

1

3

High-throughput

0.407

High

251227

RNBP6
Ran-binding protein 6

1

14

High-throughput

0.407

High

262529

MCE1
mRNA-capping enzyme

1

1

High-throughput

0.407

High

317864

LTN1
E3 ubiquitin-protein ligase listerin

1

2

High-throughput

0.407

High

334032

SMC2
Structural maintenance of chromosomes protein 2

1

5

High-throughput

0.407

High

351122

ECD
Protein ecdysoneless homolog

1

3

High-throughput

0.407

High

372332

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.407

High

457504

TBB5
Tubulin beta chain

1

1

High-throughput

0.407

High

718137

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

8

High-throughput

0.407

High

849361

RANG
Ran-specific GTPase-activating protein

1

3

High-throughput

0.407

High

915978

NUP98
Nuclear pore complex protein Nup98-Nup96

1

1

High-throughput

0.407

High

959604

MAX
Protein max

1

6

High-throughput

0.407

High

1085236

NU160
Nuclear pore complex protein Nup160

1

2

High-throughput

0.407

High

1121116

UBE4A
Ubiquitin conjugation factor E4 A

1

4

High-throughput

0.407

High

1123569

ZMYM3
Zinc finger MYM-type protein 3

1

3

High-throughput

0.407

High

1139739

SETB1
Histone-lysine N-methyltransferase SETDB1

1

3

High-throughput

0.407

High

1160494

SMN
Survival motor neuron protein

1

1

High-throughput

0.407

High

1206935

CEP78
Centrosomal protein of 78 kDa

1

5

High-throughput

0.407

High

1216511

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

5

High-throughput

0.407

High

1242067

TTC27
Tetratricopeptide repeat protein 27

1

5

High-throughput

0.407

High

1243613

THADA
tRNA

1

2

High-throughput

0.407

High

1243615

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

4

High-throughput

0.407

High

1243617

SETX
Probable helicase senataxin

1

4

High-throughput

0.407

High

1243621

HOOK3
Protein Hook homolog 3

1

7

High-throughput

0.407

High

1243629

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

2

High-throughput

0.407

High

1243631

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.407

High

1243632

NUP37
Nucleoporin Nup37

1

3

High-throughput

0.407

High

1243633

PJA1
E3 ubiquitin-protein ligase Praja-1

1

3

High-throughput

0.407

High

1243637

GEMI6
Gem-associated protein 6

1

2

High-throughput

0.407

High

1243644

TNPO1
Transportin-1

1

20

High-throughput

0.407

High

1243647

MID49
Mitochondrial dynamics protein MID49

1

1

High-throughput

0.407

High

1243648

GASP2
G-protein coupled receptor-associated sorting protein 2

1

2

High-throughput

0.407

High

1243649

HOOK2
Protein Hook homolog 2

1

6

High-throughput

0.407

High

1243652

MAGD4
Melanoma-associated antigen D4

1

3

High-throughput

0.407

High

1243660

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.407

High

1243661

XPO4
Exportin-4

1

9

High-throughput

0.407

High

1243664

GEMI7
Gem-associated protein 7

1

1

High-throughput

0.407

High

1243668

SMC4
Structural maintenance of chromosomes protein 4

1

5

High-throughput

0.407

High

1243670

GEMI8
Gem-associated protein 8

1

1

High-throughput

0.407

High

1243673

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.407

High

1243676

GPN3
GPN-loop GTPase 3

1

2

High-throughput

0.407

High

1243677

IPO11
Importin-11

1

20

High-throughput

0.407

High

1243678

XPO7
Exportin-7

1

15

High-throughput

0.407

High

1243679

HECD1
E3 ubiquitin-protein ligase HECTD1

1

4

High-throughput

0.407

High

1243680

DICER
Endoribonuclease Dicer

1

4

High-throughput

0.407

High

1243681

BCS1
Mitochondrial chaperone BCS1

1

4

High-throughput

0.407

High

1243682

SGT1
Protein SGT1 homolog

1

4

High-throughput

0.407

High

1243683

TNPO3
Transportin-3

1

20

High-throughput

0.407

High

300174

GLRX3
Glutaredoxin-3

1

0

High-throughput

0.232

Low

701174

PSB5
Proteasome subunit beta type-5

1

0

High-throughput

0.232

Low

1102405

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.232

Low

1212161

DPS1
All trans-polyprenyl-diphosphate synthase PDSS1

1

0

High-throughput

0.232

Low

1232755

CPIN1
Anamorsin

1

0

High-throughput

0.232

Low

1239412

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.232

Low

1243624

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.232

Low

1243636

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.232

Low

1243662

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025