HitPredict

Interactor 1: TELT (O15273)
Telethonin (Titin cap protein)
Gene: TCAP

Interactor 2: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	18157088, 31391242, 15967462
Identification Methods	two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030018 - Z disc GO:0031432 - titin binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 167 Hs			1 353
+	Rn
		61803 A6HIS0_RAT (1-167): 9.42e-106: 301: 91.02		TRI63_RAT (1-326): 2.25e-80: 251: 92.33
+	Hs
		174309 TELT_HUMAN (1-167): 1.54e-107: 305: 100.00		TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37
+	Hs
		174310 TELT_HUMAN (1-167): 1.54e-107: 305: 100.00		TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78