HitPredict

Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: TET2 (Q6N021)
Methylcytosine dioxygenase TET2 (EC 1.14.11.80)
Gene: TET2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.727

Property	Details
Experiments	29735542, 30404004, 25416956, 23222540, 23353889
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006493 - protein O-linked glycosylation GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1046 Hs			1 2002
+	Hs
		91449 OGT1_HUMAN (1-1046): 0: 969: 100.00		E7EQS8_HUMAN (1-2002): 0: 3138: 100.00
+	Mm
		1117016 OGT1_MOUSE (1-1046): 0: 970: 99.62		TET2_MOUSE (1-2002): 0: 2728: 57.59
+	Hs
		174457 OGT1_HUMAN (1-1046): 0: 969: 100.00		TET3_HUMAN (890-2002): 0: 854: 38.53
+	Hs
		175056 OGT1_HUMAN (1-1046): 0: 969: 100.00		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		195821 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		TET3_HUMAN (890-2002): 0: 854: 38.53