HitPredict

Interactor 1: PLXB2 (O15031)
Plexin-B2 (MM1)
Gene: PLXNB2

Interactor 2: RAB9A (P51151)
Ras-related protein Rab-9A (EC 3.6.5.2)
Gene: RAB9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Plexin_cytopl~Ras, Plexin_RBD~Ras, Ras~TIG
Common GO terms	GO:0005886 - plasma membrane GO:0006898 - receptor-mediated endocytosis GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1838 Hs			1 201
+	Hs
		175369 PLXB2_HUMAN (1-1838): 0: 2439: 100.00		RAB35_HUMAN (1-201): 2.77e-88: 259: 36.72
+	Hs
		1145161 PLXA1_HUMAN (12-1831): 0: 2077: 32.31		RAB35_HUMAN (1-201): 2.77e-88: 259: 36.72
+	Hs
		901659 PLXA1_HUMAN (12-1831): 0: 2077: 32.31		RAB7A_HUMAN (2-200): 5.13e-74: 223: 50.24
+	Hs
		1145100 SEM4C_HUMAN (1-570): 2.68e-139: 456: 18.82		RAB35_HUMAN (1-201): 2.77e-88: 259: 36.72
+	Hs
		902052 SEM4C_HUMAN (1-570): 2.68e-139: 456: 18.82		RAB9A_HUMAN (1-201): 3.87e-83: 246: 100.00
+	Hs
		976545 SEM4C_HUMAN (1-570): 2.68e-139: 456: 18.82		RB11A_HUMAN (3-201): 1.32e-74: 225: 35.38
+	Hs
		901547 SEM4C_HUMAN (1-570): 2.68e-139: 456: 18.82		RAB7A_HUMAN (2-200): 5.13e-74: 223: 50.24
+	Mm
		976717 SEM4A_MOUSE (23-608): 1.43e-138: 451: 18.43		RB11A_MOUSE (3-201): 1.32e-74: 225: 35.38