HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 667 Hs			1 768
+	Hs
		1042797 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042481 TRIM9_HUMAN (1-659): 6.49e-114: 359: 23.84		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041564 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042604 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041873 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1033366 BT1A1_HUMAN (383-659): 2.21e-80: 266: 23.81		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042145 TRI41_HUMAN (1-655): 3.11e-77: 260: 13.81		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041546 TRI14_HUMAN (152-652): 3.33e-73: 244: 18.90		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042477 TRIM8_HUMAN (4-405): 5.33e-72: 244: 20.10		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042975 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043071 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043424 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1041187 TRIM9_HUMAN (1-659): 6.49e-114: 359: 23.84		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		311856 TRI16_HUMAN (82-650): 6.16e-71: 242: 18.37		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1041461 TRIM9_HUMAN (1-659): 6.49e-114: 359: 23.84		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041060 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041371 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1040974 TRI14_HUMAN (152-652): 3.33e-73: 244: 18.90		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1171101 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		311866 TRI16_HUMAN (82-650): 6.16e-71: 242: 18.37		CUL5_HUMAN (25-768): 0: 597: 23.77