HitPredict

Interactor 1: TMPS2 (O15393)
Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
Gene: TMPRSS2

Interactor 2: TMPS2 (O15393)
Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
Gene: TMPRSS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 34709727, 36949045
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SRCR_2~Trypsin, Trypsin~Trypsin
Common GO terms GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
and 5 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 492
Hs

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Last updated: 15 Jul 2024