HitPredict

Interactor 1: NCAM2 (O15394)
Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2)
Gene: NCAM2

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hormone_recep~fn3
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 837 Hs			1 530
+	Hs
		369436 CNTN2_HUMAN (18-654): 1.58e-56: 212: 16.98		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		587103 CNTN2_MOUSE (18-654): 1.83e-54: 206: 17.44		ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72
+	Hs
		1268524 PXDN_HUMAN (25-300): 9e-18: 90.9: 26.32		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		874396 ROBO2_HUMAN (21-583): 7.95e-57: 214: 15.90		NR1H2_HUMAN (49-499): 2.78e-103: 319: 20.86
+	Hs
		611509 ROBO2_HUMAN (21-583): 7.95e-57: 214: 15.90		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		957553 PGBM_HUMAN (185-326): 1.31e-10: 67.8: 22.76		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1264774 TITIN_HUMAN (681-822): 1.85e-09: 64: 8.73		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370124 PXDN_HUMAN (25-300): 9e-18: 90.9: 26.32		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370105 TITIN_HUMAN (681-822): 1.85e-09: 64: 8.73		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377720 MXRA5_HUMAN (461-683): 9.4e-10: 64.8: 9.29		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377539 TITIN_HUMAN (681-822): 1.85e-09: 64: 8.73		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487205 DCC_HUMAN (19-691): 9.45e-44: 174: 12.31		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59