HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: S1PR4 (O95977)
Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6)
Gene: S1PR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 384
+	Hs
		178109 IPO8_HUMAN (1-1037): 0: 846: 100.00		S1PR1_HUMAN (1-377): 1.6e-69: 225: 36.62
+	Hs
		178120 IPO8_HUMAN (1-1037): 0: 846: 100.00		APJ_HUMAN (16-373): 7.1e-67: 218: 19.00
+	Hs
		312181 IPO7_HUMAN (1-1031): 0: 819: 64.57		S1PR1_HUMAN (1-377): 1.6e-69: 225: 36.62
+	Hs
		155526 TNPO2_HUMAN (12-883): 9.66e-136: 433: 12.21		S1PR1_HUMAN (1-377): 1.6e-69: 225: 36.62
+	Hs
		723119 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		OPRM_HUMAN (5-367): 3.11e-76: 242: 14.36
+	Hs
		666357 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		NK3R_HUMAN (9-359): 3.11e-67: 221: 16.25
+	Hs
		598764 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		S1PR1_HUMAN (1-377): 1.6e-69: 225: 36.62
+	Hs
		328409 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		S1PR4_HUMAN (1-384): 4.64e-67: 218: 100.00
+	Hs
		723430 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		APJ_HUMAN (16-373): 7.1e-67: 218: 19.00
+	Hs
		328374 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		S1PR4_HUMAN (1-384): 4.64e-67: 218: 100.00
+	Hs
		429042 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		ADRB2_HUMAN (16-352): 1.03e-73: 236: 17.91