HitPredict

Interactor 1: STX7 (O15400)
Syntaxin-7
Gene: STX7

Interactor 2: GOSR1 (O95249)
Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)
Gene: GOSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0005484 - SNAP receptor activity GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 250
+	Hs
		92384 STX7_HUMAN (1-261): 9.25e-70: 217: 100.00		E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20
+	Hs
		309600 STX12_HUMAN (10-244): 3.42e-58: 188: 54.01		GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00
+	Hs
		92395 STX12_HUMAN (10-244): 3.42e-58: 188: 54.01		E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20
+	Hs
		309582 STX3_HUMAN (4-237): 2.81e-52: 173: 23.33		GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00
+	Hs
		92391 STX3_HUMAN (4-237): 2.81e-52: 173: 23.33		E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20
+	Dm
		1098098 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		GOSR1_DROME (5-250): 8.4e-72: 221: 45.75
+	Dm
		1178784 Q7K0X9_DROME (10-256): 4.5e-44: 152: 38.85		GOSR1_DROME (5-250): 8.4e-72: 221: 45.75
+	Dm
		1364301 Q9VU45_DROME (10-260): 1.85e-43: 150: 23.41		GOSR1_DROME (5-250): 8.4e-72: 221: 45.75
+	Sc
		699196 PEP12_YEAST (62-236): 5.45e-11: 63.2: 25.68		GOSR1_YEAST (36-246): 6.41e-56: 180: 24.06